Results 111 to 120 of about 3,591,939 (354)
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The NASA Aviation Safety Reporting System [PDF]
This is the fourteenth in a series of reports based on safety-related incidents submitted to the NASA Aviation Safety Reporting System by pilots, controllers, and, occasionally, other participants in the National Aviation System (refs. 1-13).
core +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
The 17th IEEE International Conference on Systems and Systems Engineering [Conference Reports] [PDF]
, 2022 Celal Savur, Ferat Sahin
openalex +1 more source
A safer place for patients: learning to improve patient safety [PDF]
, 2005 1 Every day over one million people are treated successfully by National Health Service (NHS) acute, ambulance and mental health trusts. However, healthcare relies on a range of complex interactions of people, skills, technologies and drugs, and ...
Bourne, J. +5 more
core
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Report of consultation support system for people with higher brain dysfunction
, 2012 Yasuhiko Shirayama, Yasoichi Nakajima
openalex +2 more sources
Position reporting system using small satellites [PDF]
A system able to provide position reporting and monitoring services for mobile applications represents a natural complement to the Global Positioning System (GPS) navigation system.
Graziani, F., Pavesi, B., Rondinelli, G.
core +1 more source
, 1969 Weight Control System, a set of linked computer programs which provides weight and balance reports from magnetic tape files, provides weight control and reporting on launch vehicle programs.
Dyer, A., Jr. +2 more
core +1 more source
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source