Results 231 to 240 of about 20,217,519 (294)

Comprehensive analysis of etrasimod-related adverse events based on the FDA Adverse Event Reporting System database. [PDF]

Indian J Pharmacol
Zhou ZR, Zhang WJ, Zhao XY, Shen Y, Zhan Q, Sun J.   +5 more
europepmc   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Job Problems in Suicide: National Violent Death Reporting System, 2020-2022. [PDF]

Am J Prev Med
Tiesman HM, Marsh SM, Lyons BH, Blair JM.   +3 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Neurological Adverse Events Associated With Immune Checkpoint Inhibitors Identified Through Disproportionality Analysis of the FDA Adverse Event Reporting System. [PDF]

Cancer Med
Chen T, Shu K, Xiao H, Yuan Y, Zhang F, Liu Y.   +5 more
europepmc   +1 more source

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

Molecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad, Silvio Carlo Ermanno Tosatto, Emanuela Leonardi   +2 more
wiley   +1 more source

Overcoming the curse of knowledge: guidelines for reporting system-specific details of host infection and migration dynamics. [PDF]

Mov Ecol
Binning SA, Shaw AK.
europepmc   +1 more source

Risk factors for drug-related cachexia: an analysis based on the FDA adverse event reporting system (FAERS) from 2004 to 2025. [PDF]

Front Pharmacol
Huang L, Dong S, Zhang Q, Ni J.
europepmc   +1 more source

Real world pharmacovigilance study of FDA adverse event reporting system events for Spiriva Respimat. [PDF]

Front Med (Lausanne)
Chen K, Zhao S, Deng W, Ma Q, Xiao H.
europepmc   +1 more source