Results 111 to 120 of about 11,798,829 (295)
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
FEBS Letters, EarlyView.We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Impending ice age of assisted reproductive technology
F&S Reports, 2020 Pietro Bortoletto, M.D.
doaj +1 more source
A Review of the Potential Impacts of the Métis Human Resources Development Agreements in Canada [PDF]
Since 1999, thousands of Métis have received training and found employment through Métis Human Resources Development Agreements (MHRDAs). We estimate MHRDA activities’ annual fiscal impact, which includes higher tax revenue,lower government transfers ...
Andrew Sharpe, Jean-François Arsenault
core
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Economic Security in Nova Scotia [PDF]
The report uses an aggregate index, based on security from the economic risks imposed by four key factors – unemployment, illness, old age, and single parenthood – to examine trends in economic security in Nova Scotia from 1981 to 2007. It concludes that
Andrew Sharpe, Lars Osberg
core
FEBS Letters, EarlyView.The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Celebrating our one-year anniversary
Cell Reports SustainabilityMelissa Plail, Lu Liu, Richard Thompson
doaj +1 more source
Reading beyond the Classroom: The Effects of Extensive Reading at USTA, Tunja
HOW, 2009 The purpose of this study was to observe and describe the effects of applying extensive reading to a group of fifth level English students at Universidad Santo Tomás de Aquino and be accepted into the English Program.
Nery Yolanda Ruíz de Guerrero +1 more
doaj
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Urban green space, more than just an aesthetic
Cell Reports SustainabilityMelissa Plail, Richard Thompson, Lu Liu
doaj +1 more source