Results 161 to 170 of about 25,080,468 (342)
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
A sustainable and inclusive urban future
Cell Reports SustainabilityLu Liu, Melissa Plail
doaj +1 more source
The Economic Crises Through the Lens of Economic Well-being [PDF]
This report looks at how the economic crisis has unfolded in Canada and what will be the impacts on economic wellbeing. The shortfall is estimated to be approximately $12,000 ($2007) per capita. In other words, given no economic crisis, GDP per capita in
Andrew Sharpe, Jean-François Arsenault
core
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Mortality risk in relation to diet quality assessed by the 2023 nutri-score nutrient profiling model: a prospective analysis. [PDF]
Eur J NutrKhoury N +17 more
europepmc +1 more source
A Review of the Potential Impacts of the Métis Human Resources Development Agreements in Canada [PDF]
Since 1999, thousands of Métis have received training and found employment through Métis Human Resources Development Agreements (MHRDAs). We estimate MHRDA activities’ annual fiscal impact, which includes higher tax revenue,lower government transfers ...
Andrew Sharpe, Jean-François Arsenault
core
FEBS Letters, EarlyView.Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes +4 more
wiley +1 more source
The State of Knowledge on the Role and Impact of Labour Market Information: A Survey of the International Evidence [PDF]
This report provides a critical examination of the international literature on the role and impact of labour market information (LMI). The purpose of this exercise is to assess the current state of knowledge on the role and impact of LMI and to identify ...
Alexander Murray
core
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source