Results 191 to 200 of about 11,798,829 (295)

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

Molecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff, Manuela Moritz, Dennis Eggert, Anna Worthmann, Joerg Heeren, Henrike Zech, Till S. Clauditz, Waldemar Wilczak, Hartmut Schlüter, Christian S. Betz, Arne Böttcher, Jan Hahn   +11 more
wiley   +1 more source

Increase in Poison Center Reports Linked to Kratom-Containing Kava Products - National Poison Data System, United States, 2000-2025.

MMWR Morb Mortal Wkly Rep
Towers EB, Williams IL, Holstege CP, Farah R.   +3 more
europepmc   +1 more source

Toward Automating the Summarization of Cancer Pathology Reports Using Large Language Models to Improve Clinical Usability. [PDF]

JCO Clin Cancer Inform
Liu Y, John J, Sarkar S, Zakkar A, Kinkopf P, Teo PT, Abazeed ME.   +6 more
europepmc   +1 more source

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Increases in Kratom-Related Reports to Poison Centers - National Poison Data System, United States, 2015-2025.

MMWR Morb Mortal Wkly Rep
Towers EB, Thomas YT, Holstege CP, Farah R.   +3 more
europepmc   +1 more source

Retraction Note: Hybrid deep learning framework for cardiovascular disease diagnosis and prognosis using GAN, LSTM, GRU, VARMA, and deep DynaQ network. [PDF]

Sci Rep
A V, J A.
europepmc   +1 more source

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Assessment of clinical and neuroimaging efficacy of treatment targeting tau pathology in mild cognitive impairment and mild to moderate Alzheimer's disease with hydromethylthionine mesylate using external control data. [PDF]

J Prev Alzheimers Dis
Schelter BO, Shiells H, Lo S, Nazlee N, Evans E, Bentham P, Gauthier S, Zetterberg H, Wilcock GK, Froelich L, Burns A, MacSweeney E, Ballard C, Yu JT, Choon TS, Asvatourian V, Muehlemann N, Priel J, Kook K, Sullivan T, Downie D, Miller S, Pringle C, Storey JMD, Baddeley T, Harrington CR, Staff R, Sandu AL, Hull C, Stefanacci R, Wischik CM, Alzheimer's Disease Neuroimaging Initiative.   +31 more
europepmc   +1 more source

Book reports

Computers & Mathematics with Applications, 1984
openaire   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

Molecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat, Aslihan Kucuk, Omer Erdogan, Samed Ozer, Bensu Kozan, Tugba Cuceli, Erkan Gumus, Evrim Cevik, Ozge Cevik   +8 more
wiley   +1 more source