Results 101 to 110 of about 6,759,250 (289)
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Environmental management activities of an infrastructure development project: the case of Beris Dam, Malaysia [PDF]
Development projects need to integrate environmental dimensions into project management functions to ensure successful implementation of environmental management and control practices throughout the development process.
Asyirah Abdul Rahim, +2 more
core
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
The informatics pathway for hospital infection quality control monitoring
ObjectiveTo analyze the results and current status of hospital infection monitoring and quality control work at a tertiary specialized cancer hospital, providing references for further improvement of HAI monitoring quality.MethodsCombined information ...
Hui Wang +7 more
doaj +1 more source
Trends in Skills Requirements and Work-Related Issues [PDF]
[Excerpt] The Skills and Employment Survey (SES) provides an up-to-date picture of employee perspectives across a range of themes relating to work that they are doing.
Eurofound
core +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
大学トレーニングセンターにおけるトレーニング器具の衛生状況について [PDF]
University training center users include those attempting to improve their health. There are reports of a tendency of annual increase in the number of elderly people visiting fitness clubs.
田中 淳, 畑島 紀昭
core +1 more source
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source

