Tailored Vascular Approach in Robot-Assisted Nephroureterectomy for a Horseshoe Kidney: A Case Report. [PDF]
Kambe T +7 more
europepmc +1 more source
Epigenetic reprogramming of lineage switching in cancer
Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
A report on quality control and safety is given with regards to the trial An update is foreseen to be given at the end of the project D55 The following tasks will be checked and implementedo Appointment of NICI Clinical Trial Manager NICI Data Manager and local Clinical Study TeamsoStart of study preparation by ICI Clinical Trial Manager NICI Data
openaire +1 more source
Effect of Stellate Ganglion Block in Relieving Postoperative Pain After Surgery: A Systematic Review and Meta-Analysis. [PDF]
Xu S, Zhang Z, Wu T, Shen Q.
europepmc +1 more source
The microbiome in human skin aging
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Correction: Epimedin C attenuates airway inflammation and remodeling in Asthma by intervening M2 macrophage polarization via modulating the PI3K/Akt/mTOR signaling pathway. [PDF]
Zhang Z +8 more
europepmc +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Rate Versus Rhythm Control in a Multimorbid Patient With Tachy-Brady Syndrome: Evaluation of Clinical Outcomes and Pacing Dependency. [PDF]
Fakak R, Nordahl E, Moutiris J.
europepmc +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
[Expression of Concern] Antitumor activity of Notch‑1 inhibition in human colorectal carcinoma cells. [PDF]
Liao W +6 more
europepmc +1 more source

