Results 121 to 130 of about 200,201 (287)
Advanced Science, EarlyView.Radiotherapy induces tumor cells to release microparticles (RT‐MPs) into the circulation. The mitochondrial DNA carried by these RT‐MPs activates the STING/NLRP3/GSDMD axis in splenic neutrophils, triggering IL‐1β secretion. This, in turn, enhances dendritic cell function and facilitates the formation of cytotoxic T lymphocytes, thereby promoting ...
Yan Hu +18 more
wiley +1 more source
Material‐Induced Nuclear Deformation Controls Chromatin Architecture in Adipose Stem Cells
Advanced Science, EarlyView.Tuning cell and cytoskeleton mechanics modulated nuclear shape and heterochromatin organization in ASCs. Distinct cytoskeletal architectures induced nuclear morphologies from oblate to prolate ellipsoids. Large elongated cells with a structured actin cap exhibited high nuclear strain, driving nuclear envelope deformation and heterochromatin ...
Carlo F. Natale +6 more
wiley +1 more source
Advanced Science, EarlyView.Resorbable impedance sensors are successfully implanted into porcine small intestinal anastomoses. Impedance was recorded for 2 hours prior, and 2 hours following ischemia induction, and a significant drop in tissue impedance was observed. Abstract Anastomotic failure remains one of the most severe complications in gastrointestinal surgery.
Dennis Wahl +12 more
wiley +1 more source
Firm entry, product repositioning and welfare [PDF]
We show that the entry of a second firm in a horizontally differentiated market (ala Hotelling) may harm consumers as prices increase and consumer's surplus possibly decrease.
Eleftherios Zacharias
core +3 more sources
OBUSight: Clinically Aligned Generative AI for Ophthalmic Ultrasound Interpretation and Diagnosis
Advanced Science, EarlyView.OBUSight, a clinically aligned generative AI model that jointly generates reports and predicts diseases through multimodal semantic alignment, was trained and validated on a large multicenter dataset. OBUSight outperformed eight state‐of‐the‐art models, provided clinically reliable reports, enhanced diagnostic efficiency, and achieved performance ...
Xiaocong Liu +17 more
wiley +1 more source
Repositioning Religious Organization Activism in The Digital Era
Al-AlbabThe rise of the digital world poses a challenge to the position of religious organizations. This is evident in the emergence of new authorities, both individuals and groups, outside traditional religious structures.
Ach Tijani, Abdul Muin Banyal
doaj +1 more source
Advanced Science, EarlyView.A miniaturized deaminase SsdAtox was scanned with AlphaFold to identify DNA binding pocket hot spots. Site‐saturation mutagenesis at gatekeeper residue K31 yielded ten‐fold activity enhancement. Trinity Screen, an E. coli‐based three‐in‐one platform selecting for high activity and reduced double‐strand breaks, enabled combinatorial evolution at DNA ...
Ryeo Gang Son +2 more
wiley +1 more source
Photothermal Transport for Guiding Nanoparticles Through the Vitreous Humor
Advanced Science, EarlyView.Nanosecond laser irradiation of the clinically approved dye indocyanine green (ICG) enables light‐guided nanoparticle transport within the vitreous humor. The combined use of ICG and pulsed laser illumination induces localized convection and thermophoresis, directing particles toward illuminated regions.
Léa Guerassimoff +9 more
wiley +1 more source
GerokomosRESUMEN Objetivo: El objetivo que se plantea en este trabajo de revisión es responder a la pregunta: ¿Son los cambios posturales efectivos en la prevención de las úlceras por presión?
Pablo López-Casanova +3 more
doaj
DNA‐Guided Robust Single‐Protein Electronic Readout
Advanced Science, EarlyView.Electronic measurements of single proteins can reveal fundamental insights into their structure, dynamics, and interactions, but reproducibility is severely limited by the intrinsic structural heterogeneity of proteins combined with uncontrolled molecular orientation and electrode contact geometries.
Ziyi Ju +3 more
wiley +1 more source