Results 11 to 20 of about 200,201 (287)
Complementary Approaches to Existing Target Based Drug Discovery for Identifying Novel Drug Targets
Biomedicines, 2016 In the past decade, it was observed that the relationship between the emerging New Molecular Entities and the quantum of R&D investment has not been favorable.
Suhas Vasaikar +3 more
doaj +1 more source
Biomedicines, 2020 Adrenocortical carcinoma (ACC) presents a high risk of relapse and metastases with outcomes not improving despite extensive research and new targeted therapies.
Anida Hasanovic +4 more
doaj +1 more source
Preventing pressure ulcers in aged care by auditing, and changing, work practices
Asian Journal of Medical Sciences, 2022 Background: Two nurse consultants concerned with ongoing pressure ulcer development in a 44-bed residential aged care facility in Sydney, Australia, audited pressure ulcers and the use of air mattresses.
Catherine Sharp , Julie Campbell
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Factors Associated With Urgent-Start Peritoneal Dialysis Catheter Complications in ESRD
Kidney International Reports, 2020 Introduction: Urgent-start peritoneal dialysis (PD) in patients with newly diagnosed end-stage renal disease (ESRD) is a well-tolerated alternative to hemodialysis (HD).
José L. Hernández-Castillo +7 more
doaj +1 more source
Rapid chromosome territory relocation by nuclear motor activity in response to serum removal in primary human fibroblasts [PDF]
, 2010 This article has been made available through the Brunel Open Access Publishing Fund.Background: Radial chromosome positioning in interphase nuclei is nonrandom and can alter according to developmental, differentiation, proliferation, or disease status.
Amira, M +3 more
core +2 more sources
ILM Flap Repositioning for Persistent Macular Hole
Case Reports in Ophthalmology, 2022 We present a case of a persistent macular hole which was initially treated by pars plana vitrectomy with the inverted ILM flap technique. In a second procedure, the internal limiting membrane (ILM) flap was mobilized from its perifoveal adherence to the ...
Gregor Kastl, Peter Heidenkummer
doaj +1 more source
Drug Repositioning: An Opportunity to Develop Novel Treatments for Alzheimer’s Disease
Pharmaceuticals, 2013 Alzheimer’s Disease (AD) is the most common cause of dementia, affecting approximately two thirds of the 35 million people worldwide with the condition. Despite this, effective treatments are lacking, and there are no drugs that elicit disease modifying ...
Clive Ballard +2 more
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Antibiotics, 2023 Paracoccidioidomycosis (PCM) is a fungal disease caused by organisms of the genus Paracoccidioides spp. The treatment of the disease is lengthy and includes several adverse effects.
Olivia Basso Rocha +5 more
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Asymptotic Analysis of the Paradox in Log-Stretch Dip Moveout [PDF]
, 2002 There exists a paradox in dip moveout (DMO) in seismic data processing. The paradox is why Notfors and Godfrey's approximate time log-stretched DMO can produce better impulse responses than the full log DMO, and why Hale's f-k DMO is correct although it ...
Yang, Xin-She, Zhou, Binzhong
core +2 more sources
Viruses, 2021 The immunological findings from autopsies, biopsies, and various studies in COVID-19 patients show that the major cause of morbidity and mortality in COVID-19 is excess immune response resulting in hyper-inflammation. With the objective to review various
Apparao Peddapalli +5 more
doaj +1 more source