Results 221 to 230 of about 2,545,734 (238)

BCR::ABL1‐Induced Enhancer Reprogramming Uncovers Hypersensitivity of Ph+B‐ALL Cells to Enhancer‐Targeting Drugs

Advanced Science, EarlyView.
Ng et al. show that the BCR::ABL1 kinase that drives the lymphoid leukemia Ph+B‐ALL modulates enhancer function by coopting signaling‐inducible transcription factors such as MYC, STAT5, and ETV5. BCR::ABL1 thereby promotes the transcriptional program driving and defining this leukemia and renders Ph+B‐ALL cells hypersensitive to enhancer‐inhibiting ...
Han Leng Ng, Trudy Lee Glaser, Jintao Zhu, Mark E. Robinson, Kadriye N. Cosgun, Valeriya Malysheva, Ozgen Deniz, Nicholas T. Crump, Kaiyue Helian, Andrew J. Innes, Richard Burt, Li Sun, George John, Haibin Zhou, Atsunori Kaneshige, Longchuan Bai, Shaomeng Wang, Mikhail Spivakov, Markus Müschen, Niklas Feldhahn   +19 more
wiley   +1 more source

Correction to: Comprehensive analysis of scRNA-seq and bulk RNA-seq reveals the non-cardiomyocytes heterogeneity and novel cell populations in dilated cardiomyopathy. [PDF]

J Transl Med
He S, Li C, Lu M, Lin F, Hu S, Zhang J, Peng L, Li L.   +7 more
europepmc   +1 more source

A Perspective on Interactive Theorem Provers in Physics

Advanced Science, EarlyView.
Into an interactive theorem provers (ITPs), one can write mathematical definitions, theorems and proofs, and the correctness of those results is automatically checked. This perspective goes over the best usage of ITPs within physics and motivates the open‐source community run project PhysLean, the aim of which is to be a library for digitalized physics
Joseph Tooby‐Smith
wiley   +1 more source

Diversity Patterns of Domestic Herbivore Viruses in China Reveal Transmission Dynamics with Disease Management Implications

Advanced Science, EarlyView.
This study performs pan‐viromic profiling of 14,529 samples from 5,710 domestic herbivores across five Chinese provinces, establishing the DhCN‐Virome (1,085,360 viral metagenomes). It reveals species/sample‐specific viromic signatures and cross‐species transmission dynamics, aiding unified disease control.
Yue Sun, Yong Li, Bagen Temur, Yuanqing Lin, Yuhang Liu, Le Yi, Zheng Sun, Gang Zhang, Jun Li, Yu Guo, Linchuan Li, Jinshan Cai, Wenliang Tian, Gen Meng, Lingling Jiang, Min Fang, Fuying Ding, Xuezhang Zhou, Changchun Tu, Biao He   +19 more
wiley   +1 more source

Organ‐Specific and Conserved Regulatory Logic Orchestrates Gene Expression in the Embryonic Mesothelium

Advanced Science, EarlyView.
Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang, Nicola Smart, Andia Nicole Redpath, Joaquim Miguel Vieira   +3 more
wiley   +1 more source

Microsatellite/SSR dataset: characterization of pear cultivars of the German Fruit Genebank. [PDF]

Sci Data
Broschewitz L, Schramm B, Flachowsky H, Schulte E, Höfer M.   +4 more
europepmc   +1 more source

Assessing the applicability of big data driven urban vibrancy analysis in mixed urbanized-depopulated contexts: a case study of a Japanese city. [PDF]

Sci Rep
Ishii Y, Hayakawa K.
europepmc   +1 more source

Research Code Sharing in Support of Gold Standard Science. [PDF]

J Diabetes Sci Technol
Klonoff DC, Espinoza J, Mader JK, Heinemann L, Cobelli C, Kerr D, Kovatchev B, Najafi B, Prahalad P, Zheng Y, Shao MM, Scheideman AF, DuNova AY, Kohn M, Umpierrez GE, Wong TY, Abdel Malek A, Agus MSD, Ahn DT, AlSaad R, Al-Sofiani ME, Armstrong D, Arnold MA, Bee YM, Bequette BW, Bellazzi R, Cengiz E, Chase JG, Chen H, Chen JY, Cichosz SL, Cinar A, Clements MA, Close KL, Cuadros J, Contreras I, Datta G, Dhatariya K, Doyle FJ, Drincic A, Facchinetti A, Fleming GA, Foreman J, Gabbay MAL, Gutierrez-Osuna R, Healey E, Hoang TD, Jacobs PG, Kulzer B, La Belle J, Lee AY, Lee CS, Lee WA, Liepmann D, Maahs D, Mathioudakis N, Meo SA, Metwally AA, Misra S, Mohan V, Moon SJ, Raeder H, Rhee C, Rhee EJ, Scheinker D, Shah VN, Sheng B, Snyder MP, Sode K, Spanakis EK, Svensson J, Vaswani N, Vareth M, Vehi J, Wallia A, Waki K, Wang T, Williams E, Wolf RM, Wong JC, Yeshiwas S, Zilbermint M, Shah SN.   +82 more
europepmc   +1 more source

UMUD: a web application for easy access to musculoskeletal ultrasonography datasets. [PDF]

BMC Med Imaging
Ritsche P, Sarto F, Santini F, Leitner C, Franchi MV, Faude O, Finni T, Seynnes O, Cronin N.   +8 more
europepmc   +1 more source