Results 41 to 50 of about 2,528,445 (262)
AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Polimedia: Using advanced screencasting for effective e-learning content production
In this paper we present Polimedia, a system designed to help teachers producing high quality e-learning content without technological knowledge. We achieve this by using a special TV-like recording studio that gets teachers' video and learning material ...
Carlos Turro +3 more
doaj +1 more source
Consortial routes to effective repositories [PDF]
A consortial approach to the establishment of repository services can help a group of Higher Education Institutions (HEIs) to share costs, share technology and share expertise.
Moyle, M., Proudfoot, R.
core
Security functions for a file repository [PDF]
When personal machines are incorporated into distributed\ud systems a new mixture of threats is exposed.\ud The security effort in the MobyDick project\ud is aimed at understanding how privacy can be protected\ud in this new environment.
Helme, Arne, Stabell-Kulo, Tage
core +3 more sources
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern +7 more
wiley +1 more source
Augmenting tomato functional genomics with a genome-wide induced genetic variation resource
Induced mutations accelerate crop improvement by providing novel disease resistance and yield alleles. However, the alleles with no perceptible phenotype but have an altered function remain hidden in mutagenized plants.
Prateek Gupta +6 more
doaj +1 more source
The Specifics of the Elective “School of Leadership” Using Repositories of Online Resources
Objective. Modern online library resources play an important role in the organisation and conduct of the School of Leadership elective. The purpose of this study is to consider the peculiarities of conducting the elective “School of Leadership” for ...
N. O. MYKYTENKO, A. M. KOTLOVSKYI
doaj +1 more source
BlogForever: D3.1 Preservation Strategy Report [PDF]
This report describes preservation planning approaches and strategies recommended by the BlogForever project as a core component of a weblog repository design.
Arango-Docio, Silvia +9 more
core +1 more source
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker +16 more
wiley +1 more source
Redefining the Institutional Repository [PDF]
Institutional Repositories have grown in importance over the last 10 years to offer a core University and Library service, however, their role is developing faster now than it has ever done.
Keene, Chris
core +1 more source

