Results 51 to 60 of about 2,545,734 (238)

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

BlogForever: D3.1 Preservation Strategy Report [PDF]

, 2013
This report describes preservation planning approaches and strategies recommended by the BlogForever project as a core component of a weblog repository design.
Arango-Docio, Silvia, Banos, Vangelis, Garcia Llopis, Jaime, Kalb, Hendrik, Kim, Yunhyong, Pinsent, Ed, Ross, Seamus, Sleeman, Patricia, Stepanyan, Karen, Trochidis, Illias   +9 more
core   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Implementation of a standardized information management system into activity of scientific and technical library

Автоматизация технологических и бизнес-процессов, 2018
An effective solution to the tasks of preserving and accessing electronic documentation requires software applications, namely an electronic archive within the information management system of the organization.
A. Bohdanov, V. M. Plotnikov, K. V. Smirnova, I. I. Zinchenko   +3 more
doaj   +1 more source

Now we are 13. Open Research Online becomes a teenager! [PDF]

, 2015
The history of the Open University (UK) institutional repository (Open Research Online) is one of changing requirements as defined by its research community, institutional administrators and external HE policy.
Biggs, Chris, Dowson, Nicola, Stiles, Alan   +2 more
core  

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Digital library of scientific forums organized by the Faculty of Mathematics and Informatics of the University "St. Cyril and St. Methodius "- Veliko Tarnovo

Digital Presentation and Preservation of Cultural and Scientific Heritage, 2016
The increasing needs to expand access to research results and insufficient opportunities for publication in printed issues put a serious challenge to the scientific community. The aim of the paper is to mark the first step towards solving this problem in
Tsvetanka Georgieva Trifonova, Kaloyan Zdravkov   +1 more
doaj   +1 more source

Overview of molecular signatures of senescence and associated resources: pros and cons

FEBS Open Bio, EarlyView.
Cells can enter a stress response state termed cellular senescence that is involved in various diseases and aging. Detecting these cells is challenging due to the lack of universal biomarkers. This review presents the current state of senescence identification, from biomarkers to molecular signatures, compares tools and approaches, and highlights ...
Orestis A. Ntintas, Sylvia Vagena, Pavlos Pantelis, Giorgos Theocharous, Russel Petty, Konstantinos Evangelou, Vassilis G. Gorgoulis   +6 more
wiley   +1 more source

γ-Radiation induces region-specific subcellular alterations of amyotrophic lateral sclerosis and frontotemporal dementia markers in swine brain

Scientific Reports
Low-dose radiation (LDR) effects on the brain have been poorly investigated. Studies have also questioned whether radiation increases ALS risk. We assessed the expression levels of a series of proteins associated with ALS and ALS-FTD in the brains of ...
Diego Iacono, Erin K. Murphy, Daniel P. Perl, Regina M. Day   +3 more
doaj   +1 more source

Serological and molecular investigation of suspected chickenpox cases from India, 2016–2025

Journal of Infection and Public Health
Background: Varicella, commonly known as chickenpox is a neglected disease in India with numerous outbreaks reported in the last decade. Unfortunately, varicella vaccine is not included in India’s Universal Immunization Program (UIP), and active ...
Sunil R. Vaidya, Sarang S. Kamble, Madhukar B. Kamble, Roben P. George, Pankaj G. Pandey, Atul M. Walimbe   +5 more
doaj   +1 more source