Results 61 to 70 of about 2,528,445 (262)
Molecular Oncology, EarlyView.Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz +15 more
wiley +1 more source
Digital Presentation and Preservation of Cultural and Scientific Heritage, 2016 The increasing needs to expand access to research results and insufficient opportunities for publication in printed issues put a serious challenge to the scientific community. The aim of the paper is to mark the first step towards solving this problem in
Tsvetanka Georgieva Trifonova +1 more
doaj +1 more source
Microbial Effects on Repository Performance [PDF]
, 2010 This report presents a critical review of the international literature on microbial effects in and around a deep geological repository for higher activity wastes.
Humphreys, Paul +2 more
core
ATF4‐mediated stress response as a therapeutic vulnerability in chordoma
Molecular Oncology, EarlyView.We screened 5 chordoma cell lines against 100+ inhibitors of epigenetic and metabolic pathways and kinases and identified halofuginone, a tRNA synthetase inhibitor. Mechanistically halofuginone induces an integrated stress response, with eIF2alpha phosphorylation, activation of ATF4 and its target genes CHOP, ASNS, INHBE leading to cell death ...
Lucia Cottone +11 more
wiley +1 more source
Using the Lens database for staff publications
Journal of the Medical Library Association, 2020 In a rapidly changing landscape, many health sciences libraries are looking to increase the support they provide for research in their organization. The Lens database is a free platform for enabling discovery of both scholarly and patent literature.
Rob Penfold
doaj +1 more source
Molecular Oncology, EarlyView.The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg +43 more
wiley +1 more source
Serological and molecular investigation of suspected chickenpox cases from India, 2016–2025
Journal of Infection and Public HealthBackground: Varicella, commonly known as chickenpox is a neglected disease in India with numerous outbreaks reported in the last decade. Unfortunately, varicella vaccine is not included in India’s Universal Immunization Program (UIP), and active ...
Sunil R. Vaidya +5 more
doaj +1 more source
Conimbricenses.Org: an open-access online repository on the Philosophical tradition in Coimbra
DEDiCA, 2018 Only a few Institutions in Europe can praise to be such an important chapter of the European culture like the University of Coimbra, and its unique philosophical tradition, already started in the Middle Ages, is still nowadays a crucial passage to ...
Simone Guidi
doaj +1 more source
Data Science Journal, 2020 The paper will give an overview of national infrastructure for digital repositories, Digital Academic Archives and Repositories (DABAR), and its role as technology steward in raising awareness about research data management (RDM) and promoting good ...
Kristina Posavec +2 more
doaj +1 more source
Developing the repository manager community [PDF]
, 2013 This paper describes activities which have taken place within the UK institutional repository (IR) sector focusing on developing a community of practice through the sharing of experiences and best practice.
Budden, Yvonne C. +3 more
core +1 more source