Results 121 to 130 of about 1,776,164 (255)
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Représentations du Discours dans un entretien écrit : un parcours génétique [PDF]
International audienceCet article analyse la représentation du discours dans l'écriture d'un entretien avec Antoine Culioli qui constitue l'ouvrage Variations sur la linguistique.
Doquet, Claire
core +2 more sources
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Inertia tensor and cross product In n-dimensions space
We demonstrated using an elementary method that the inertia tensor of a material point and the cross product of two vectors were only possible in a three or seven dimensional space.
Hassan, Mehdi Hage
core +1 more source
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
"Meddling with Royal Hearts": Interiority and Privanza (1598-1643) [PDF]
This paper studies how seventeenth-century writers in Spain elaborated different conceptions of interiority in connection with the intimacy they imagined between the king and his favorite or privado.
Patino-Loira, Javier
core
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
Asymptotic bias of some election methods [PDF]
Consider an election where N seats are distributed among parties with proportions p_1,...,p_m of the votes. We study, for the common divisor and quota methods, the asymptotic distribution, and in particular the mean, of the seat excess of a party, i.e ...
Janson, Svante
core
Structural biology of ferritin nanocages
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source

