Results 101 to 110 of about 527,014 (251)

Premières Représentations. [PDF]

open access: yes
Transcript of PREMIÈRES REPRÉSENTATIONS by Catulle Mendès, appearing in LE JOURNAL, 9 mai 1907 ...
Mendès, Catulle
core   +4 more sources

Ceux qui regardent font le paysage : les Inuit d’Umiujaq et le parc national Tursujuq (Nunavik)

open access: yesTéoros, 2012
Le tourisme fabrique des vitrines attractives. Celle du Nunavik est constituée d’un chapelet de villages et de vastes parcs nationaux en cours de création, avec des archétypes paysagers brandis par les guides touristiques et les portails Internet.
Fabienne Joliet
doaj  

Contraste sociolinguistique, dynamique socioculturelle et variation dialectale, Cas de deux familles d’Adrar installées à Tlemcen

open access: yesAltralang Journal, 2023
Sociolinguistic Contrast between the North and the South of Algeria – Sociocultural Dynamics and Dialectal Variations, Case of Two Families from Adrar settled in Tlemcen ABSTRACT: The Maghreb countries are known for their linguistic diversity due to ...
Mohamed DJENNANE, Sid Ahmed KHELLADI
doaj  

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Interactions entre les différents protagonistes d’un do [PDF]

open access: yesCinema & Território, 2018
La méthode du documentaire en lien avec les interactions possibles entre ses protagonistes (filmeur, filmé et spectateur) va dans un premier temps aider à définir les identités de ces participants à la construction du film documentaire. Puis, ce sont les
Natacha CYRULNIK
doaj  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Représentations moléculaires et systèmes sémiotiques

open access: yes, 2009
International audienceLa représentation des connaissances sous forme de signes et de symboles favorise l'apprentissage et l'enseignement. Duval a proposé un cadre théorique sémiotique pour les mathématiques, articulé en trois axes : les relations entre ...
Le Maréchal, Jean-François   +1 more
core  

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

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