Results 71 to 80 of about 872,521 (356)

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

On the regular representation of solvable Lie groups with open coadjoint quasi-orbits [PDF]

, 2023
Ingrid Beltiţă, Daniel Beltiţă
openalex   +1 more source

Computing Representations of a Lie Group via the Universal Enveloping Algebra

Journal of Symbolic Computation, 1998
Computing representations on the enveloping algebra was developed by physicists (e.g. \textit{B. Gruber} and \textit{A. U. Klimyk} [J. Math. Phys. 25, 755-764 (1984; Zbl 0548.17005)]), but their methods work only for very simple Lie algebras. This new algorithm constructs explicit \textit{principal matrices} and avoids difficulties with commutators ...
Feinsilver, Philip, Schott, René
openaire   +2 more sources

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Representations of differential operators on a Lie group

Journal of Functional Analysis, 1975
AbstractIn this paper we apply the theory of second-order partial differential operators with nonnegative characteristic form to representations of Lie groups. We are concerned with a continuous representation U of a Lie group G in a Banach space B. Let E be the enveloping algebra of G, and let dU be the infinitesimal homomorphism of E into operators ...
openaire   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

A classification of coherent state representations of unimodular Lie groups [PDF]

Bulletin of the American Mathematical Society, 1991
Let \(G\) be a connected Lie group and \((T,H)\) a unitary representation of \(G\) on a complex Hilbert space \(H\). Assume that \((T,H)\) is nontrivial \((\dim H>1)\). By a coherent state orbit (CS orbit) for \((T,H)\) the author means a complex orbit of \(G\) on the projective space \(P(H)\). The author calls \((T,H)\) a coherent state representation
openaire   +3 more sources

Survivin and Aurora Kinase A control cell fate decisions during mitosis

Molecular Oncology, EarlyView.
Aurora A interacts with survivin during mitosis and regulates its centromeric role. Loss of Aurora A activity mislocalises survivin, the CPC and BubR1, leading to disruption of the spindle checkpoint and triggering premature mitotic exit, which we refer to as ‘mitotic slippage’.
Hana Abdelkabir, Shalitha Wickrama Arachchige, Sally P. Wheatley   +2 more
wiley   +1 more source

Special Unipotent Representations of Simple Linear Lie Groups of Type A

Acta Mathematica Sinica, English Series
To appear in Acta Mathematica Sinica, English ...
Barbasch, D., Ma, J., Sun, B., Zhu, C.
openaire   +4 more sources

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source