Results 91 to 100 of about 2,531,593 (291)

Gravity‐Dependent Modulation of Downbeat Nystagmus: Insights From Velocity‐Storage Dysfunction

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Downbeat nystagmus varies with head position, a phenomenon termed gravity‐dependent modulation. We aimed to clarify its mechanism using a velocity‐storage model. Methods In 10 patients with downbeat nystagmus due to cerebellar disorders, we recorded eye movements at different pitch‐ and roll‐axis head positions.
Ji‐Hyung Park, Eun‐Hyuk Choi, Jorge Otero‐Millan, David S. Zee, Jeong‐Yoon Choi, Ji‐Soo Kim   +5 more
wiley   +1 more source

Researching transformation at a South African university - ethical dilemmas in the politics of representation [PDF]

, 2011
This is an Accepted Manuscript of an article published by Taylor & Francis in Studies in Higher Education on 18 Jan 2011, available online: http://www.tandfonline.com/10.1080/03075070903545066.This article focuses on the complexity of researching ...
Ismail, Salma
core   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

A politics of place framework for unravelling peri-urban conflict: An example of peri-urban Sydney, Australia

Journal of Urban Management, 2018
Peri-urban areas are increasingly described as ‘third’ spaces with unique characteristics, in opposition to spaces awaiting urban development. However, in many peri-urban areas the process of defining what this ‘third’ space is, is triggering conflict ...
Laure-Elise Ruoso, Roel Plant
doaj   +1 more source

Stage‐Dependent β‐Synuclein Links MRI and Cognitive Decline in Alzheimer's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Synaptic degeneration drives cognitive decline in Alzheimer's disease (AD), but synaptic biomarkers are scarce. Brain‐enriched β‐synuclein emerged as a synaptic damage marker. We investigated its diagnostic, prognostic, and structural correlates across the AD continuum.
Ulaş Ay, Merve Alaylioglu, Erdi Sahin, Sanem Sultan Yoruk Oner, Gulce Iskan, Gulce Cosku Yilmaz Cakan, Gozde Kizilates‐Evin, Emre Hari, Elif Kurt, Erdinc Dursun, Basar Bilgic, Hasmet Hanagasi, Hakan Gurvit, Tamer Demiralp, Duygu Gezen‐Ak, Bedia Samanci   +15 more
wiley   +1 more source

The politics of divide: representation and the Torres Strait diaspora

, 2012
Australia's Indigenous population is comprised of two related, but distinct cultural groups – Aboriginal people and Torres Strait Islanders. The two groups have a shared history dating back to thousands of years of cultural exchange, trade and travel ...
Watkin Lui, Felecia
core   +1 more source

Más allá de enfoques utópicos y distópicos sobre innovación democrática. Beyond Utopian and Dystopian approaches to democratic innovation

Recerca: Revista de Pensament i Anàlisi, 2019
This paper discusses the myths regarding both the conceptualization and the expected effects that are implicitly or explicitly presented in analyses of the so-called ‘democratic innovations’, that is, the new institutions that aim to increase public ...
Gisela Zaremberg, Yanina Welp
doaj   +1 more source

Women's contested politics of presence : learning from the experiences of Pakistani women parliamentarians [PDF]

This study provides a case study of women’s political representation in the National Parliament of Pakistan, where a particular form of the quota approach has been adapted in a highly gendered political context.
Syed, Shaheen Ashraf Shah
core  

The Price of Precision: A Critical Review of Molecular Diagnostics in Glioma, From Guidelines to Global Disparities

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Gliomas have undergone a profound redefinition over the past decade, transitioning from morphology‐based entities to biologically coherent diseases defined by molecular alterations. The 2021 WHO Classification of Tumors of the Central Nervous System and its 2022 update formalize this shift, establishing integrated diagnosis as the global ...
Maria Guarnaccia, Sebastiano Cavallaro
wiley   +1 more source

Stasis and Politics: On the Forgotten Role of Violence

Eidos. A Journal for Philosophy of Culture, 2019
One of the major questions emerging in present-day reflections on politics is related to violence and its relation to institutional order and law. In the paper, an issue of concern for a very particular form of political conflict, that is, civil war, is ...
Urszula Zbrzeźniak
doaj   +1 more source