Results 111 to 120 of about 3,100,522 (340)
Manipulating Representations [PDF]
Biosemiotics, 2011 The present paper proposes a definition for the complex polysemic concepts of consciousness and awareness (in humans as well as in other species), and puts forward the idea of a progressive ontological development of consciousness from a state of 'childhood' awareness, in order to explain that humans are not only able to manipulate objects, but also ...
openaire +2 more sources
FEBS Letters, EarlyView.Three‐dimensional (3D) biological systems have become key tools in lymphoma research, offering reliable in vitro and ex vivo platforms to explore pathogenesis and support precision medicine. This review highlights current 3D non‐Hodgkin lymphoma models, detailing their features, advantages, and limitations, and provides a broad perspective on future ...
Carla Faria +3 more
wiley +1 more source
Spheres, 2017 We are witnessing an acceleration of the deployment of digital technologies in border regimes as well as in migratory practices. This does not necessarily make borders ‘smarter’, but it points to spiraling dynamics between border and migration practices to which digital technologies prove central.
openaire +5 more sources
The Observable Representation [PDF]
Entropy, 2019 The observable representation (OR) is an embedding of the space on which a stochastic dynamics is taking place into a low dimensional Euclidean space. The most significant feature of the OR is that it respects the dynamics. Examples are given in several areas: the definition of a phase transition (including metastable phases), random walks in which the
openaire +4 more sources
From omics to AI—mapping the pathogenic pathways in type 2 diabetes
FEBS Letters, EarlyView.Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan +2 more
wiley +1 more source
ERBIN limits epithelial cell plasticity via suppression of TGF‐β signaling
FEBS Letters, EarlyView.In breast and lung cancer patients, low ERBIN expression correlates with poor clinical outcomes. Here, we show that ERBIN inhibits TGF‐β‐induced epithelial‐to‐mesenchymal transition in NMuMG breast and A549 lung adenocarcinoma cell lines. ERBIN suppresses TGF‐β/SMAD signaling and reduces TGF‐β‐induced ERK phosphorylation.
Chao Li +3 more
wiley +1 more source
On representations of selfmappings [PDF]
Proceedings of the American Mathematical Society, 1970 It is shown in this note that every “mild” self mapping f : X → X f:X \to X of a compact Hausdorff space X X into itself can be represented by the product ( Y , g ) × ( Z , h ) (Y,g) \times (Z,h)
openaire +3 more sources
Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells
FEBS Letters, EarlyView.Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan +2 more
wiley +1 more source
Nuevo mundo - Mundos Nuevos, 2018 The sixties were years in which the number of young people in Mexico grew, and also a time when this population diversified. Given this fact, statements issued by government institutions that contained dictations and statements about their duties and ...
Katia Escalante Monroy
doaj +1 more source
FEBS Letters, EarlyView.C‐mannosylation is a unique form of protein glycosylation. In this study, we demonstrated that ADAMTS1 is C‐mannosylated at Trp562 and Trp565 in human testicular germ cell tumor NEC8 cells. We found that C‐mannosylation of ADAMTS1 is essential for its secretion, processing, enzymatic activity, and ability to promote vasculogenic mimicry. These findings
Takato Kobayashi +5 more
wiley +1 more source