Results 81 to 90 of about 383,454 (268)

Representation Levels Within Knowledge Representation [PDF]

open access: yes, 2007
Representation of knowledge is used to store and retrieve informational data in a machine. Since meaningcannot be directly stored in the computer; this work proposes a series of levels of representation. The meaning of the data is transformed to a format that the machine can use to store and retrieve knowledge.
Heather D. Pfeiffer   +1 more
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva   +5 more
wiley   +1 more source

Voix, corps et « amours nomades » : Les femmes du désert et les ambiguïtés du regard d’Isabelle Eberhardt

open access: yesViatica
This article examines Isabelle Eberhardt’s last work, the travelogue Sud Oranais, in order to shed some light on her views and representations of the “women of the desert”. Her perspective proves to be quite complex and ambiguous, mixing the depreciatory
Vanezia Pârlea
doaj   +1 more source

LANGUAGE REFORMS AT ALGERIAN UNIVERSITIES: REPRESENTATIONS, MOTIVATIONS AND PRACTICES [PDF]

open access: yesAnalele Universităţii din Craiova. Psihologie, Pedagogie
This paper examines the adoption of English as the language of teaching in the technical programs of Algerian universities in 2023 from a didactic and sociolinguistic perspective.
Riadh GHESSIL, Sarah SLIMANI
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Alegorías, metáforas y símbolos en el cine sobre la Revolución mexicana

open access: yesCaravelle, 2011
This work intends to analyze the way Mexican cinema has built allegoric images of the Mexican Revolution through sequences or key scenes which, far from being a collection of official images, show the complexity of the Mexican filmmakers’ vision of the ...
Alvaro Vázquez Mantecón
doaj   +1 more source

On Medial Representations [PDF]

open access: yes, 2008
During the last half century, medial representations of objects have been involved in many biological and physical theories, and computer scientists have designed suitable algorithms for their computation. Aim of this paper is to provide a short, non-comprehensive, survey of the most common medial representation systems.
openaire   +3 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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