Results 101 to 110 of about 26,581 (300)

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

open access: yesFEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon   +6 more
wiley   +1 more source

CARTOGRAFIAS GEOGRÁFICAS: O QUE PODE UM MAPA...

open access: yesRevista Geographia, 2018
Resumo: Pensar o mapa é pensá-lo como o agenciamento de forças, de linhas/corpos que se afetam e apontam para sentidos de localização e orientação espacial.
Djeovani Roos   +1 more
doaj   +1 more source

A class of infinite convex geometries [PDF]

open access: yes, 2015
Various characterizations of finite convex geometries are well known. This note provides similar characterizations for possibly infinite convex geometries whose lattice of closed sets is strongly coatomic and lower continuous. Some classes of examples of
Adaricheva, Kira, Nation, J. B.
core   +2 more sources

Tumor‐stromal crosstalk and macrophage enrichment are associated with chemotherapy response in bladder cancer

open access: yesFEBS Open Bio, EarlyView.
Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold   +11 more
wiley   +1 more source

TEMPORALITY OF THE NARRATIVE OF CONTEMPORARY TRAVEL LITERATURE (Based on Cees Nooteboom’s work) [PDF]

open access: yesAlfred Nobel University Journal of Philology
The article examines the temporality of narrative in the discourse of contemporary travel literature in the context of socio-cultural dynamics associated with the digitalization of life forms, socio-cultural interactions and new models of comprehension,
Olena I. Kretova, Pavlo V. Kretov
doaj   +1 more source

Sahara or Sahel? The fuzzy geography of terrorism in West Africa [PDF]

open access: yes
Since the mid-2000s, terrorism has pushed the peripheries of West Africa into the news and the public eye. While the political implications of this phenomenon have been extensively documented, most commentators have adopted a zonal approach to terrorism ...
RETAILLE Denis, WALTHER Olivier
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

open access: yesFEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Examining Elements of Middle Eastern Dystopia: A Comparative Study of Vaght-e Taghsir and Frankenstein in Baghdad [PDF]

open access: yesتاریخ ادبیات
IntroductionThe term “dystopia” was coined in 1868 in reference to authoritarian societies, and it often relates to totalitarian regimes (Vieira, 2010: 5&16; Baccolini & Moylan, 2013: 4-7). It was first used in English literature in 1747, albeit with the
Zein Alabedeen Asaad, Mohammad Ragheb
doaj   +1 more source

Diagramming Irréversible [PDF]

open access: yes, 2010
Diagrammatically plots spatiality and the conjunction of time and space in Gaspar Noé's Irréversible (2002) and contrasts his post-modern vision of twisted masculinity with W.B.
Hester, Diarmuid
core  

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

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