Results 131 to 140 of about 67,579 (318)

Landscape Space: Integration of Culture and Nature [PDF]

open access: yesمسکن و محیط روستا, 2012
Landscape Space: Integration of Culture and Nature   Authors:     Dr. Shahram Pourdeihimi, MArch(SBU), PhD(Leeds)   Professor, school of architecture and Planning, Shahid Beheshti University     Sassan Seyedkalal, PhD Candidate(SBU), MArch(SBU), MLA ...
Sassan Seyedkalal, Shahram Pourdeihimi
doaj  

Space, Time and Nature: The process and the myth [PDF]

open access: yes, 2015
The article fits into the debate regarding space, time and nature in dialogue with the world lived by subjects that build up themselves or are built as mythological heroes, source of speech and spacial concrete practices.
Araújo, Maxem Luiz   +3 more
core  

Diabetes‐induced vascular calcification is associated with low pyrophosphate and its oral supplementation prevents calcification in diabetic mice

open access: yesFEBS Open Bio, EarlyView.
Induction of diabetes in three different mouse strains uniformly resulted in an increase in TNAP activity and a reduction in pyrophosphate (PPi) in the circulation. Inhibition of TNAP restored plasma PPi. Diabetes‐induced calcification in the media layer of the aorta was detected only in the Abcc6−/− strain, which is predisposed to ectopic ...
Krisztina Fülöp   +13 more
wiley   +1 more source

The scale of sense : spatial extent and multimodal urban design [PDF]

open access: yes, 2008
This paper is derived from the work of the UK AHRC/EPSRC 'Designing for the 21st Century' research project Multimodal Representation of Urban Space. This research group seeks to establish a new form of notation for urban design which pays attention to ...
Lucas, Raymond   +2 more
core  

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

open access: yesFEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Analysis of Treacher Collins syndrome 4‐associated mutations in Schizosaccharomyces pombe

open access: yesFEBS Open Bio, EarlyView.
Fission yeast models carrying Treacher Collins syndrome type 4‐associated mutations reveal that impaired processivity of RNA polymerase I leads to defective rRNA transcription. This study highlights the essential role of a conserved arginine residue in Pol I elongation and provides mechanistic insight into the pathogenesis of ribosomopathies.
Kei Kawakami, Hiroaki Kato
wiley   +1 more source

"Eating Out", spatiality, temporality and sociality. A database for China, Indonesia, Japan, Malaysia, Singapore and France. [PDF]

open access: yesFront Nutr, 2023
Mognard E   +16 more
europepmc   +1 more source

TMC4 localizes to multiple taste cell types in the mouse taste papillae

open access: yesFEBS Open Bio, EarlyView.
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata   +6 more
wiley   +1 more source

Economical representation of spatial networks

open access: yesPNAS Nexus
Abstract Network representation is crucial across various scientific, societal, technological, and artistic domains. The primary goal is to highlight patterns out of nodes interconnected by edges that are easy to understand, facilitate communication, and support decision-making.
Fabrizio De Vico Fallani   +1 more
openaire   +2 more sources

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

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