Results 91 to 100 of about 89,660 (330)
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
Brussels Studies, 2015 The spatial analysis of a literary text published in the mid 19th century allows a rediscovery of the panoramic literature genre and the wealth of information it provides about the urban context in which it was born.
Tatiana Debroux +3 more
doaj +1 more source
Thinking About Events: A Pragmatist Account of the Objects of Episodic Hypothetical Thought [PDF]
, 2018 The debate over the objects of episodic memory has for some time been stalled, with few alternatives to familiar forms of direct and indirect realism being advanced.
Michaelian, Kourken, Sant’Anna, André
core +3 more sources
Formal Representation of Temporal Expressions
EPiC Series in Language and Linguistics, 2019 In this paper we address the semantics of temporal expressions in natural language (such as vchera,’yesterday’, shestnadcatogo maja, ’on the 16th of May’, tri dnja ’three days’) and the way they interact with some other manifestations of temporality (such as functioning of prepositions and aspectual verb forms).
openaire +2 more sources
FEBS Letters, EarlyView.We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley +1 more source
Une antinomie durkheimienne… et au-delà
Temporalités, 2008 For sociologists, time has always been an intellectual enigma. Lately, another concept – temporality – has been preferred in contemporary sociological research.
Michel Lallement
doaj +1 more source
Reading “On Time and Being” to Construct the ‘Missing’ Division III of Being and Time – or “time and Being” – [PDF]
, 2018 This paper will articulate the conditions of thinking about the transition of Division II in Heidegger’s Being and Time in order to imagine the architecture of the missing Division III, which never appeared in the published Part I of Being and Time.
Sampath, Rajesh
core
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Clio y Asociados, 2020 This study is about the representations of the rhythms of change in the process of teaching/learning of high school students.
Daniela Cartes Pinto, Joan Pagès Blanch
doaj +1 more source
Molecular Oncology, EarlyView.The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués +3 more
wiley +1 more source