Results 51 to 60 of about 61,987 (289)
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
The Phenomenology of Religious Life: From Primary Christianity to Eastern Christianity [PDF]
, 2015 In this paper I attempt a reading of Heidegger’s interpretations of St. Paul’s Epistles in light of the distinction between Eastern and Western thought.
Bejinariu, Alexandru
core +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Frontiers in Energy ResearchThe present paper introduces a novel method for identifying voltage sags in time-variant power distribution networks, effectively addressing the challenges arising from the temporal variability of network topology and data. The proposed method is founded
KeWen Li +3 more
doaj +1 more source
Physicality and Cooperative Design [PDF]
, 2008 CSCW researchers have increasingly come to realize that material work setting and its population of artefacts play a crucial part in coordination of distributed or co-located work.
A. Dix +27 more
core +5 more sources
Time after time – circadian clocks through the lens of oscillator theory
FEBS Letters, EarlyView.Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo +2 more
wiley +1 more source
Reading “On Time and Being” to Construct the ‘Missing’ Division III of Being and Time – or “time and Being” – [PDF]
, 2018 This paper will articulate the conditions of thinking about the transition of Division II in Heidegger’s Being and Time in order to imagine the architecture of the missing Division III, which never appeared in the published Part I of Being and Time.
Sampath, Rajesh
core
Conceptual Modelling and The Quality of Ontologies: Endurantism Vs. Perdurantism
, 2012 Ontologies are key enablers for sharing precise and machine-understandable semantics among different applications and parties. Yet, for ontologies to meet these expectations, their quality must be of a good standard.
Al Asswad +4 more
core +1 more source
Chronoscopes: A Theory of Underspecified Temporal Representations [PDF]
, 2007 Representation and reasoning about time and events is a fundamental aspect of our cognitive abilities and intrinsic to our construal of the structure of our personal and historical lives and recall of past experiences. This talk describes an abstract device called a Chronoscope, that allows a temporal representation (a set of events and their temporal ...
openaire +3 more sources
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source