Results 91 to 100 of about 120,380 (313)

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Message from CPA MOJ Representative [Release of Detainees in Iraq]

open access: yes, 2012
List of detainees to be released. All names redacted.Made available in DSpace on 2012-10-10T14:36:57Z (GMT). No. of bitstreams: 3 manifest.xml: 4127 bytes, checksum: aa3681a6dbcec252748879d8b64fea95 (MD5) 00935text.txt: 12129 bytes, checksum ...

core  

SOME THOUGHTS CONCERNING AUTHORITY IN THE ROMAN-CATHOLIC CHURCH [PDF]

open access: yesВестник Православного Свято-Тихоновского гуманитарного университета: Серия I. Богословие, философия, 2010
The paper dealt with the topic of authority in the church affirm s that the exercise of legitimate authority is granted by god, whose divine son iounded the church.
R. CHRISTIAN, OP
doaj  

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Capturing the Justice Judgment: An Application of the Theory of Representative Design in two Policy Capturing Studies in Organizational Justice [PDF]

open access: yes, 2011
An understanding of how justice judgments are formed is essential knowledge for practitioners given the adverse consequences which may arise due to perceptions of unfairness.
GERMAN, HAYLEY,CLAIRE   +1 more
core  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

The Great Barrier Reef Representative Areas Program Poster 2004

open access: yes, 2004
The Great Barrier Reef Representative Areas Program - The planning process in ...

core  

Conclusion on the peer review of the pesticide risk assessment of confirmatory data submitted for the active substance ethoprophos

open access: yes, 2013
The conclusions of the European Food Safety Authority (EFSA) following the peer review of the initial risk assessment carried out by the competent authority of the rapporteur Member State the United Kingdom, for the pesticide active substance ethoprophos
European Food Safety Authority
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

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