Results 121 to 130 of about 1,233,073 (308)
Kedudukan dan Kewenangan Dewan Perwakilan Daerah dalam Sistem Ketatanegaraan Indonesia [PDF]
, 2011 Functioned as a regional representative council, DPD possessing a regional representative character principally has a broader representative character compared to DPR (Legislative Assembly). It is because its representative dimensions are based on all of
Nirahua, S. E. (Salmon)
core
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
State of New York Public Employment Relations Board Decisions from December 23, 1983 [PDF]
, 1982 12_17_1982_PERB_BD_DecisionsOCR.pdf: 82 downloads, before Oct.
New York State Public Employment Relations Board
core +5 more sources
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
FEBS Letters, EarlyView.Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source
Dewan Perwakilan Daerah Menurut UUD 1945 Dan Penerapan Sistem Bikameral Dalam Lembaga Perwakilan Indonesia [PDF]
, 2007 Formally, Indonesia adopts bicameral system as there are the House of Representatives (DPR) and the Regional Representatives Council (DPD). However, structurally, it could be deemed ad tricameral, as there are three representative bodies available ...
Bardjo, B. (Bardjo)
core
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Money-Based versus Exchange Rate-Based Stabilization with Endogenous Fiscal Policy [PDF]
We present a standard intertemporal model in which fiscal policy is determined by an optimizing but non-benevolent fiscal authority. If the fiscal authority is impatient, a money-based stabilization provides more fiscal discipline and higher welfare for ...
Aaron Tornell, Andres Velasco
core