Results 161 to 170 of about 1,238,477 (309)

A local-authority specific definition of research: Results from a Delphi study. [PDF]

Public Health Pract (Oxf)
Brown LM, Sowden S, Briggs ADM, Dennington-Price A, Dutta V, Hampshaw S, Humphreys E, Johns T, Levitas A, Murphy R, Needham K, Renwick L, Hayes L.   +12 more
europepmc   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Beyond polarization for coexistence with biodiversity: Reply to Bruskotter et al. (2025). [PDF]

Conserv Biol
Pooley S.
europepmc   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

Molecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel, Peyman Zarrineh, Nathnael T. Tuffa, Jigar H. Sheth, Sumitra Mohan, Mudassar Iqbal, Sankari Nagarajan   +6 more
wiley   +1 more source

Identity interweaving, act boundaries, illusion and reality interweaving: A study of visual narratives of scientists and citizen scientists through AI. [PDF]

PLoS One
He Y, Jian X, Zhang W, Jin X.
europepmc   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Preparation, molecular docking, and biological evaluation of radioiodinated cefaclor for inflammation detection. [PDF]

BMC Pharmacol Toxicol
Hussien H, El Refaye MS, Aglan H, Challan SB, Khater SI.   +4 more
europepmc   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Reconstruction of the Authority of the Papuan People's Assembly Based on the Principles of Siyasah Syar'iyyah: A Study of the Function of Cultural Representation

Al-Adalah
This research is motivated by the ongoing issue of limited authority held by the Papuan People’s Assembly (Majelis Rakyat Papua/MRP) as a cultural representative institution established through the Special Autonomy framework to protect the identity and ...
Lukman Ansar, Sabar Podu, Lisma Lisma, Satriadi Satriadi, Zulfadli Zulfadli, Dandi Wahyudin, Andi Miftahul Maulidil Mursyid   +6 more
doaj  

Energy and macronutrient intakes of Montenegrin adults: insights from the EFSA EU Menu National Survey (2017-2022). [PDF]

Front Nutr
Orahovac A, Barjaktarović Labović S, Milačić A, Martinović A, Mach RL.   +4 more
europepmc   +1 more source