Results 191 to 200 of about 112,387 (262)

A Deep Learning-Driven Framework Integrating Organoid-Based Functional Validation Identifies Universal Neoantigens from Recurrent Glioma Mutations. [PDF]

Cancer Res
Wang C, Sun T, He Y, Yu M, Pan CQ, Hu H, Sun Y, Wang D, Cui Z, Zhang J, Zhai Y, Shi Z, Li Z, Xu M, Oh YT, Jiang T, Xu Z, Li G, Zhang J, Zhang W.   +19 more
europepmc   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Reforming the white coat economy: judicial evidence and institutional implications from China's healthcare anti-corruption campaign. [PDF]

Front Public Health
Shen Z, Guo J, Li J, Chen Z, Tang Y.
europepmc   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Nisin and rutin as potential coating agents for iron oxide nanoparticles for enhanced theranostic applications against cancer. [PDF]

Sci Rep
Saad OA, Elfiky AA, Fathy MM, Ibrahim IM, Ibrahim MA, Elgharib AM, Ali OA, Ezat AA.   +7 more
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Emergency medical preparedness and response for mass gatherings: Papua New Guinea emergency medical team's experience during Pope Francis's 2024 visit. [PDF]

Western Pac Surveill Response J
Oli U, Nou GG, Hosea R, Konigala K.
europepmc   +1 more source

Novel molecular assays for monitoring T cell function after HSCT in two siblings with variants in <i>DCLRE1C</i>. [PDF]

J Hum Immun
Lyytikäinen A, Shamshirgaran Y, Hjerpe H, Cajander S, Wahren Borgström E, Gharaghani S, Erikson E, Vonlanthen S, Marits P, Hammarsten O, Smith CIE, Fasth A, Johansson P.   +12 more
europepmc   +1 more source

Functional development of photoreceptors in human retinal organoids. [PDF]

Stem Cell Res Ther
Zhang Y, Du M, Wang YH, Li M, Jin K, Pan D, Zhang X, Jin ZB.   +7 more
europepmc   +1 more source

Adolescent and Youth Sexual Reproductive Health (AYSRH): Perceived Religious Health Assets of Churches and Their Optimization for Youth Sexual Health in South Africa's Vaal Region. [PDF]

Healthcare (Basel)
Magezi V.
europepmc   +1 more source