Results 201 to 210 of about 357,026 (288)

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Habitat prioritization for bat conservation: A case study in Vietnam. [PDF]

PLoS One
Tuan LQ, Tu VT, Tuan TA, Thong VD, Son NT, Luong NT, Vy NT, Thanh HT, Csorba G, Görföl T, Tuanmu MN.   +10 more
europepmc   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Does it mean more positive or more negative? A study on central attitudes toward homosexuality. [PDF]

Front Psychol
Guo L, Fang S, Zhang Y, Li X, Yang Y.
europepmc   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

ctDNA detectability and representativeness in seven body liquids from patients with metastatic breast cancer. [PDF]

Nat Commun
Richard F, Maetens M, Van Baelen K, Borremans K, Van Cauwenberge J, Zels G, Rousseau E, Geukens T, De Schepper M, Mahdami A, Vanderheyden E, Van Brussel T, Nguyen HL, Pabba A, Leduc S, Izci H, Bachir I, Carette C, Hatse S, Nysen M, Vermeulen P, Boeckx B, Lambrechts D, Biganzoli E, Neven P, Wildiers H, Van Den Bogaert W, Demeulemeester J, Floris G, Desmedt C.   +29 more
europepmc   +1 more source

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

FEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli, Mohammad Nour Alsamsam, Ugnė Bagdonaitė, Van Truc Vu, Chun‐Jen Huang, Polina Kuzhir, Mindaugas Zaremba, Aurimas Kopūstas, Marijonas Tutkus   +8 more
wiley   +1 more source

Sport performance in virtual worlds: a systematic review of sport simulation in neurological paralympic athletes and non-athlete populations. [PDF]

BMC Sports Sci Med Rehabil
Calabrò RS, Calderone A, Maggio MG, Speciale F, Bruschetta D, Lanza M, Quartarone A.   +6 more
europepmc   +1 more source

The representativeness of the 1999 Spanish FADN survey. [PDF]

Mora, Ricardo, San Juan Mesonada, Carlos, Torre, J. E de la   +2 more
core  

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source