Results 271 to 280 of about 424,116 (333)

Demographic Data Supporting FDA Authorization of AI Devices for Alzheimer Disease and Related Dementias.

JAMA
Chen KY, Ross JS, Cohen AB, Karlawish J, Oh ES, Gupta R.   +5 more
europepmc   +1 more source

Enhancing representativeness in population-based surveys to improve data quality and decision-making. [PDF]

Sci Rep
Rousset S, Charrier L, Bersia M, Comoretto RI, Dalmasso P.   +4 more
europepmc   +1 more source

BMI‐1 modulation and trafficking during M phase in diffuse intrinsic pontine glioma

FEBS Open Bio, EarlyView.
The schematic illustrates BMI‐1 phosphorylation during M phase, which triggers its translocation from the nucleus to the cytoplasm. In cycling cells, BMI‐1 functions within the PRC1 complex to mediate H2A K119 monoubiquitination. Following PTC596‐induced M phase arrest, phosphorylated BMI‐1 dissociates from PRC1 and is exported to the cytoplasm via its
Banlanjo Umaru, Deepak Kumar Mishra, Shiva Senthil Kumar, Hao‐Han Pang, Brendan Devine, Komal Khan, Rachid Drissi   +6 more
wiley   +1 more source

Which way? Group-based smoking and vaping cessation support for Aboriginal and Torres Strait Islander women: protocol for a non-randomised type 1 hybrid implementation study. [PDF]

BMJ Open
Booth K, Bryant J, Maddox R, Ridgeway T, Maidment S, Martiniuk AL, Chamberlain C, Eades SJ, Burchill LJ, Belfrage M, Bennett J, Doran C, Collis F, Mills Z, Foster J, Mersha AG, Roberts-Barker K, Oldmeadow C, Longbottom H, Wills K, Taylor N, Kennedy M.   +21 more
europepmc   +1 more source

Nuclear pore links Fob1‐dependent rDNA damage relocation to lifespan control

FEBS Open Bio, EarlyView.
Damaged rDNA accumulates at a specific perinuclear interface that couples nucleolar escape with nuclear envelope association. Nuclear pores at this site help inhibit Fob1‐induced rDNA instability. This spatial organization of damage handling supports a functional link between nuclear architecture, rDNA stability, and replicative lifespan in yeast.
Yamato Okada, Mina Iwaki, Kyosuke Hagiri, Rei Izumi, Masahiko Harata, Chihiro Horigome   +5 more
wiley   +1 more source

DISOBEDIENCE TO REPRESENTATIVES OF THE CORRECTIONAL INSTITUTION ADMINISTRATION: LEGAL NATURE AND DELINEATION FROM CRIMES

Aleksandr Mihajlovich Pleshakov, Gennadij Shkabin   +1 more
openalex   +2 more sources

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

The Scale-Up of a Digital Health Intervention (Healthy Beginnings for HNEKids) Targeting the First 2000 Days: Protocol for a Randomized Controlled Trial.

JMIR Res Protoc
Brown AL, Hudson N, Jackson J, Pinfold J, Wolfenden L, Nathan N, Sewter R, Kavalec S, Davies L, Young S, McCormick H, Stanley S, Delaney T, Lecathelinais C, Craven P, Redman S, Cushing E, de Mello N, Lee K, Sutherland R.   +19 more
europepmc   +1 more source

Assessing safety and efficacy in subpopulations in Alzheimer's disease clinical trials: contextualizing representativeness. [PDF]

Alzheimers Dement (N Y)
Shan G, Cummings J.
europepmc   +1 more source