Results 71 to 80 of about 185,395 (312)

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Leadership Representativeness in the Australian Union Movement [PDF]

open access: yes, 2000
This paper explores the dimensions of political and personal representativeness in the context of Australian unionism in the period since World War Two.
Bramble, T. J.
core  

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Anomalous Price Behavior Following Earnings Surprises: Does Representativeness Cause Overreaction? [PDF]

open access: yes
Behavioral Finance aims to explain empirical anomalies by introducing investor psychology as a determinant of asset pricing. This study provides strong evidence that anomalous stock price behavior following earnings announcements is due to a ...
Michael Kaestner
core  

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Landscape Representativeness Within the Network of Ecological Corridors Linking Natura 2000 Areas in Poland [PDF]

open access: yes, 2010
This paper analyses landscape representativeness within the ecological corridor network linking Natura 2000 areas in Poland. The criteria used to designate the network did not include landscape representativeness.
Gerlée, Alina
core   +3 more sources

Generations and Gender Programme Wave 1 data collection: An overview and assessment of sampling and fieldwork methods, weighting procedures, and cross-sectional representativeness

open access: yesDemographic Research, 2016
Background: The Generations and Gender Survey (GGS) was developed to stimulate the study of a broad range of topics of relevance to population scientists. So far, at least one wave of the GGS has been conducted in 19 countries.
Tineke Fokkema   +4 more
doaj   +1 more source

The impact of assembly size on representativeness

open access: yes, 2014
Choosing the number of seats in a legislature is a balancing act between efficiency and representativeness. This article focuses on representativeness and hypothesises that the larger the assembly, the higher the vote-seat proportionality, the higher the
Elklit, Jørgen, Kjær, Ulrik; id_orcid
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Representativeness of AERONET and GAW aerosol observation sites

open access: yes, 2019
A ranking of the spatial representativeness of AERONET and GAW sites, based on a high resolution global numerical simulation (OSSE)
Schutgens, Nick
core   +2 more sources

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