Results 101 to 110 of about 616,462 (316)
Civil Society Report to the Commission on Social Determinants of Health
A hundred and fifty years after his death we continue to be reminded of Virchow’s comment: “Do we not always find the diseases of the populace traceable to defects in society”?
Representatives of Civil Society
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
The Ethics of Representing Elected Representatives
Capitol Hill used to be referred to as "the last plantation."1 For the purposes of this symposium, however, I believe that it is more useful to think of Capitol Hill not in terms of the antebellum South but rather in terms of medieval Europe. Congress consists of a series of fiefdoms.
openaire +2 more sources
Key Texas Senate and House water committee chairmen discuss water issues of the 85th Legislature
Editor-in-Chief’s note: In every odd-numbered year, the Texas Legislature convenes in regular session for 140 days. With this in mind, the Texas Water Journal invited Senator Charles Perry, Chairman of the Senate Agriculture, Water & Rural Affairs ...
Sen. Charles Perry, Rep. Lyle Larson
doaj
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura +2 more
wiley +1 more source

