Results 161 to 170 of about 405,671 (296)

Simulations predict stronger CRISPRi transcriptional repression in plants for identical than heterogeneous gRNA target sites. [PDF]

Synth Biol (Oxf)
Scott H, Occhialini A, Lenaghan SC, Beal J.   +3 more
europepmc   +1 more source

Widespread microRNA repression by Myc contributes to tumorigenesis

Nature Genetics, 2008
Tsung-Cheng Chang, Duonan Yu, Yun‐Sil Lee, E. Wentzel, D. Arking, K. West, C. Dang, A. Thomas-Tikhonenko, J. Mendell   +8 more
semanticscholar   +1 more source

Small RNA Toxin‐Assisted Evolution of GC‐Preferred ErCas12a for Enhanced Genome Targeting Range

Advanced Science, EarlyView.
ErCas12a is engineered to target GC‐rich PAMs using a small RNA toxin‐aided positive screening system. The resulting variant, enErCas12a, exhibits an expanded PAM profile and facilitates efficient gene editing in both bacterial and mammalian cells, while preserving high targeting specificity for both canonical and non‐canonical PAM targets.
Zehua Chen, Junyuan Xue, Ziying Wang, Jinyuan Sun, Yinglu Cui, Tong Zhu, Huaiyi Yang, Ming Li, Bian Wu   +8 more
wiley   +1 more source

INDUCTION AND REPRESSION OF NITRATE REDUCTASE IN NEUROSPORA CRASSA [PDF]

, 1961
Stephen C. Kinsky
openalex   +1 more source

Ethylene‐Activated E3 Ubiquitin Ligase MdEAEL1 Promotes Apple Fruit Softening by Facilitating the Dissociation of Transcriptional Repressor Complexes

Advanced Science, EarlyView.
Ethylene‐activated MdEAEL1 mediates the disassembly of the MdZFP3‐MdTPL4‐MdHDA19 transcriptional repression complex, upregulating the histone acetylation levels in the promoter regions of cell wall degradation‐related genes, consequently promoting softening during storage.
Tong Li, Li Liu, Guangxin Yang, Yingcong Cai, Yingda Wang, Bowen Sun, Le Sun, Weiting Liu, Aide Wang   +8 more
wiley   +1 more source

Altered End-Product Patterns and Catabolite Repression in Escherichia coli [PDF]

, 1966
Walter J. Dobrogosz
openalex   +1 more source

Studies on Induction and Repression in Activated Sludge Systems [PDF]

, 1962
A Gaudy
openalex   +2 more sources

Immunotyping the Tumor Microenvironment Reveals Molecular Heterogeneity for Personalized Immunotherapy in Cancer

Advanced Science, EarlyView.
This study develops TMEclassifier, a machine‐learning tool that classifies cancers into three distinct subtypes—Immune exclusive (IE), immune suppressive (IS), and immune activated (IA)—which exhibit significant heterogeneity and necessitate customized therapeutic strategies.
Dongqiang Zeng, Yunfang Yu, Wenjun Qiu, Qiyun Ou, Qianqian Mao, Luyang Jiang, Jianhua Wu, Jiani Wu, Huiyan Luo, Peng Luo, Wenchao Gu, Na Huang, Siting Zheng, Shaowei Li, Yonghong Lai, Xiatong Huang, Yiran Fang, Qiongzhi Zhao, Rui Zhou, Huiying Sun, Wei Zhang, Jianping Bin, Yulin Liao, Masami Yamamoto, Tetsuya Tsukamoto, Sachiyo Nomura, Min Shi, Wangjun Liao   +27 more
wiley   +1 more source

Catabolite Repression in Antibiotic-limited Streptomycin-dependent Escherichia Coli B

, 1969
M. B. Coukell, W. J. Polglase
openalex   +1 more source

Catabolite Repression and Pyruvate Metabolism in Escherichia coli [PDF]

, 1967
Richard T. Okinaka, Walter J. Dobrogosz
openalex   +1 more source