Results 221 to 230 of about 93,471 (266)

Matrix Stiffness Orchestrates Mesenchymal Stem Cell Lineage Commitment Toward Osteogenesis and Adipogenesis Through the PIEZO1/SP1/STC2 Axis

Advanced Science, EarlyView.
Matrix stiffness directs mesenchymal stem cell lineage commitment through PIEZO1‐dependent activation of the SP1/STC2 pathway. Stiff matrices favor osteogenesis and suppress adipogenesis, whereas the loss of PIEZO1 function impairs early bone formation. STC2 retains lineage‐regulatory activity even when PIEZO1 is inactive.
Shuo Zhang, Siteng Li, Wenzhong Chen, Qingcheng Song, Haiyue Zhao, Peng Wang, Yiran Zhang, Wenquan Liang, Shaowei Zheng, Juan Wang, Wei Chen, Yanbin Zhu, Yingze Zhang   +12 more
wiley   +1 more source

RNA G-quadruplexes in oncogene regulation and as emerging targets for cancer therapy. [PDF]

Cell Commun Signal
Liu ZY, Wang XY, Gong DD, Tang X, Man CF, Zhang SQ, Fan Y.   +6 more
europepmc   +1 more source

The Effect of Ligand Reactivity and Carrier Mechanics on Thiol‐Mediated Cellular Uptake for miRNA Nano‐Drugs

Advanced Science, EarlyView.
The effect of ligand reactivity and carrier mechanics on thiol‐mediated uptake was investigated at the single‐molecule/particle level. The interaction kinetics of LA and AspA with membrane thiols were quantified; AspA is more efficient due to the higher binding affinity, greater binding stability, and more double‐disulfide binding, as well as greater ...
Zhuang Zhang, Hui Wang, Hao Zhang, Zhenkuan Cao, Zehui Liu, Siying Li, Hongda Wang, Yuping Shan   +7 more
wiley   +1 more source

Interplay between stress granule-like structures and nuclear RNA export in a heat shock-specific manner. [PDF]

Nucleic Acids Res
Jeon H, Shin D, Son Y, Park J, Lee DJ, Shim JS, Song DG, Son H.   +7 more
europepmc   +1 more source

Epigenetic regulation of vertebrate limb development: from field specification to tissue morphogenesis. [PDF]

Epigenetics
Vallejo-De Lira CM, Galván-Hernández CI, Chimal-Monroy J, Marin-Llera JC.   +3 more
europepmc   +1 more source

Triple florigenic signaling in rice promotes stem elongation via transcriptional de-repression. [PDF]

Plant J
Vicentini G, Bertagnon G, Dobetti F, Giaume F, Cazzaniga F, Baldini A, Bono GA, Maika J, Moore SS, Bignardi A, Simon R, Perrella G, Nagai K, Ashikari M, Fornara F, Brambilla V.   +15 more
europepmc   +1 more source

Plant LHP1 as a Context-Dependent Regulator of Polycomb-Associated Chromatin. [PDF]

Physiol Plant
Sarwar R, Fan X, Dong K, Geng R, Liang Y, Tan XL.   +5 more
europepmc   +1 more source

Structural characterization of the human CC2D1A fragment associated with non-syndromic intellectual disability (NSID). [PDF]

Biosci Rep
Yeh YH, Lin MG, Sun XH, Shen YY, Ling P, Hsiao CD.   +5 more
europepmc   +1 more source

Segregated, standardised, repressed: socialisation and the entrenchment of structural domination

openaire   +1 more source