Results 291 to 300 of about 2,089,944 (391)

Whole genome mutagenicity evaluation using Hawk-Seq™ demonstrates high inter-laboratory reproducibility and concordance with the transgenic rodent gene mutation assay. [PDF]

Genes Environ
Matsumura S, Hosoi S, Hirose T, Otsubo Y, Saito K, Miyazawa M, Kawade A, Hakura A, Kakiuchi D, Asakura S, Koyama N, Okada Y, Chikura S, Kimoto T, Masumura K, Suzuki T, Sugiyama KI.   +16 more
europepmc   +1 more source

Central Dysmyelination in SSADH‐Deficient Humans and Mice

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives Succinic semialdehyde dehydrogenase deficiency (SSADHD) is an inherited metabolic disorder characterized by an accumulation of γ‐aminobutyric (GABA). In addition to its synaptic role as an inhibitory neurotransmitter, GABA also plays an important role in myelination.
Itay Tokatly Latzer, Henry H. C. Lee, Edward Yang, Cesar Alves, Mariarita Bertoldi, Caitlyn Fung, Spencer V. Steele, Eren Kule, Zijie Jin, Alexander Rotenberg, Jean‐Baptiste Roullet, Phillip L. Pearl   +11 more
wiley   +1 more source

Reproducibility of Breech Progression Angle: Standardization of Transperineal Measurements and Development of Image-Based Checklist for Quality Control. [PDF]

Diagnostics (Basel)
Fidalgo AM, Aquise A, Molina FS, Youssef A, González-Vanegas O, Brunelli E, Cataneo I, Segata M, Cuerva MJ, Rolle V, Gil MM.   +10 more
europepmc   +1 more source

The rs10191329 Risk Allele Is Associated With Pronounced Retinal Layer Atrophy in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To investigate whether the rs10191329 risk allele in the DYSF–ZNF638 locus, which is implicated in central nervous system resilience rather than immune‐mediated pathology, is associated with retinal layer thinning, a biomarker of neuroaxonal damage in relapsing multiple sclerosis (RMS). Methods From a prospective observational study,
Gabriel Bsteh, Ruchi Tanavade, Nik Krajnc, Fabian Föttinger, Theresa König, Martin Krenn, Lukas Haider, Barbara Kornek, Fritz Leutmezer, Kerstin U. Ludwig, Stefan Macher, Tobias Monschein, Markus Ponleitner, Paulus Rommer, Christiane Schmied, Karin Zebenholzer, Tobias Zrzavy, Gudrun Zulehner, Franziska Di Pauli, Axel Schmidt, Harald Hegen, Berthold Pemp, Thomas Berger   +22 more
wiley   +1 more source

Repeatability, reproducibility, and agreement for three optical coherence tomography instruments. [PDF]

BMC Ophthalmol
Zhang J, Zhong M, Fan S, Chang X, Li X, Chen H, Bao J, Huang Y.   +7 more
europepmc   +1 more source

Reproducibility in Science: Improving the Standard for Basic and Preclinical Research

Circulation Research, 2015
C. Begley, J. Ioannidis
semanticscholar   +1 more source

Quantitative Iron Measurements in the Basal Ganglia of NBIA Patients Using QSM: Insights From a Tertiary Center

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurodegeneration with brain iron accumulation (NBIA) comprises rare genetic disorders characterized by predominantly extrapyramidal symptoms and iron deposition in the basal ganglia. Conventional magnetic resonance imaging (MRI) detects qualitative changes but cannot accurately quantify iron accumulation. Quantitative susceptibility
Özge Uygun, Alpay Özcan, Fuat Kaan Aras, Evrim Bozdemir, Sibel Uğur İşeri, Murat Gültekin, Nihan Hande Akçakaya, Orkhan Mammadov, Gülay Kır, Dilek İnce Günal, Neşe Tuncer, Fatma Betül Özdilek, Banu Özen Barut, Ercan Köse, Hülya Apaydın, Asuman Ali, Sultan Çağırıcı, Pınar Topaloğlu, Alp Dinçer, Zuhal Yapıcı   +19 more
wiley   +1 more source

Editorial: Environmental Enrichment: Enhancing Neural Plasticity, Resilience, and Repair

Frontiers in Behavioral Neuroscience, 2019
Amanda C. Kentner, Kelly G. Lambert, Anthony J. Hannan, Anthony J. Hannan, S. Tifffany Donaldson   +4 more
doaj   +1 more source

Reproducibility of published model-based cancer drug cost-effectiveness analyses: a study protocol for a cross-sectional analysis. [PDF]

BMJ Open
Svensson M, Siverskog J, Johansson N, Henriksson M.   +3 more
europepmc   +1 more source