Results 291 to 300 of about 1,188,104 (349)

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, Volume 15, Issue 5, Page 836-855, May 2025.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

Autonomous robotic ultrasound scanning system: a key to enhancing image analysis reproducibility and observer consistency in ultrasound imaging. [PDF]

Front Robot AI
Lin XX, Li MD, Ruan SM, Ke WP, Zhang HR, Huang H, Wu SH, Cheng MQ, Tong WJ, Hu HT, He DN, Lu RF, Lin YD, Kuang M, Lu MD, Chen LD, Huang QH, Wang W.   +17 more
europepmc   +1 more source

A potential tumor suppressor role of PLK2 in glioblastoma

FEBS Open Bio, Volume 15, Issue 5, Page 856-866, May 2025.
PLK2 was consistently downregulated in GBM tissues. Overexpression of PLK2 in GBM cell lines U87MG and U251 reduced their tumorigenic potential and enhanced cell cycle arrest and apoptosis. Suggesting that PLK2 overexpression could potentially be leveraged as a therapeutic strategy to inhibit tumor progression and enhance apoptosis, providing new ...
Xiangping Xia, Peirui Wang, Hua Xiao, Qishan Ran, Yan Li, Shengtao Yao   +5 more
wiley   +1 more source

Data sharing practices in high-impact rehabilitation journals. [PDF]

BMC Med Res Methodol
Elghzali A, Molina D, Chaudhry M, Duncan J, Elfar A, Oldham E, Dennis B, Paul E, Ford AI, Vassar M.   +9 more
europepmc   +1 more source

The Reproducibility and Accuracy of Static and Impact Torsion Tester Used for Measuring the Toughness of Highly Hardened Tool Steels

, 1964
Shunichiro Abe
openalex   +2 more sources

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, Volume 15, Issue 5, Page 773-792, May 2025.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

Use of a Silicone Mask Improves the Reproducibility of Tooth Color Assessment for Whitening Clinical Trials. [PDF]

Int J Dent
Porciani PF, Grandini S, Perra C, Porcu L, Torri V, Diomede L, Sarrica A.   +6 more
europepmc   +1 more source

Hydrogen sulfide repairs testicular damage induced by heat stress in rats

FEBS Open Bio, EarlyView.
Heat stress can cause testicular damage and affect fertility. We investigated the potential protective role of hydrogen sulfide (H2S) against heat stress‐induced testicular injury and observed that H2S donor NaHS can effectively restore testicular damage in rats by inhibiting inflammation and oxidative stress. Our results suggest that H2S might be used
Xinyu Guo, Yupeng Yin, Susu Guo, Xiaoyan Chen, Suyan Xie, Shiqin Chen, Yan Huang   +6 more
wiley   +1 more source

Influence of scanning plane on Human Spinal Cord functional Magnetic Resonance echo planar imaging. [PDF]

PLoS One
Moraschi M, Tommasin S, Maugeri L, DiNuzzo M, Cohen-Adad J, Masullo M, Mangini F, Giovannelli L, Mascali D, Gili T, Pisani V, Nocentini U, Giove F, Fratini M.   +13 more
europepmc   +1 more source

Accuracy and Reproducibility of Determination Results of Components in the Furnace Atmosphere by Gas Chromatography

, 1964
保田 正文, 益本 茂, 牧原 明由
openalex   +2 more sources