Results 221 to 230 of about 166,851,649 (309)

Assessing reproducibility of Hi-C chromatin interactions using stratum-adjusted irreproducible discovery rate. [PDF]

Bioinformatics
Xue C, Zhang F, Li Q.
europepmc   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

Diagnostic performance and inter-observer reproducibility of glomerular PLA2R immunohistochemistry in primary membranous nephropathy: a multi-laboratory blinded observer study. [PDF]

BMC Nephrol
Tougaard BG, Krag S, Gravesen E, Kristensen ME, Madsen K, Riis LB, Krustrup D, Ivarsen P.   +7 more
europepmc   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

Repeatability and reproducibility of MRI-derived radiomics on a 0.35 T MR-Linac using a tissue-mimicking phantom. [PDF]

Phys Imaging Radiat Oncol
Collard F, Herault F, Vanquin L, Gagez AL, Loussert A, Collard D, Pasquier D.   +6 more
europepmc   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source

Automated reproducibility assessments in the social and behavioral sciences using large language models

Feuerriegel S, Holtdirk T, Marcolongo P, Schulten AS, Henninger F, Rose S, Ball S, Ma B, Kreuter F, Weinmann M.   +9 more
europepmc   +1 more source

Dental age estimation in forensic odontology: a systematic review comparing traditional methods and artificial intelligence approaches. [PDF]

Front Dent Med
Lakhaouaja F, García Navarro A.
europepmc   +1 more source