The evidence and concerns about screening ultrasound for breast cancer. [PDF]
Cancer Biol MedYan H, Wang Q, Zhao F, Kang D, Qiao Y.
europepmc +1 more source
De Novo Design of Integrin α5β1 Modulating Proteins to Enhance Biomaterial Properties
Advanced Materials, EarlyView.NeoNectins are de novo‐designed miniproteins that selectively bind and stabilize the extended open form of integrin α5β1. When grafted onto biomaterials including hydrogel and titanium, they promote cell attachment and spreading in vitro and promoting tissue integration and bone growth in animal models, demonstrating broad potential for regenerative ...
Xinru Wang +25 more
wiley +1 more source
Breakthroughs and challenges of organoid models for assessing cancer immunotherapy: a cutting-edge tool for advancing personalised treatments. [PDF]
Cell Death DiscovWang Q, Yuan F, Zuo X, Li M.
europepmc +1 more source
Advanced Materials, EarlyView.Cancer metastasis begins with intravasation, a complex process involving cancer‐endothelial interactions. INVADE (Intravasation‐on‐µDevice), a biomimetic microfluidic platform enables high‐throughput analysis of intravasation under controlled conditions.
Fengtao Jiang +12 more
wiley +1 more source
Data standards for single-cell RNA-sequencing of paediatric cancer. [PDF]
Clin Transl ImmunologyXu X +4 more
europepmc +1 more source
Harnessing Photo‐Energy Conversion in Nanomaterials for Precision Theranostics
Advanced Materials, EarlyView.Harnessing photo‐energy conversion in nanomaterials enables precision theranostics through light‐driven mechanisms such as photoluminescence, photothermal, photoelectric, photoacoustic, photo‐triggered surface‐enhanced Raman scattering (SERS), and photodynamic processes. This review explores six fundamental principles of photo‐energy conversion, recent
Jingyu Shi +4 more
wiley +1 more source
SERS-based detection of DNA methylation for cancer diagnosis: Cation-mediated adsorption to silver nanoparticles. [PDF]
PLoS OneIancu SD +6 more
europepmc +1 more source
Engineering Bacterial Secretion Systems for Enhanced Tumor Imaging and Surgical Guidance
Advanced Materials, EarlyView.This study presents a novel contrast agent platform, Streptavidin Associated Salmonella (SAS), for fluorescence image guided surgery. SAS selectively colonizes tumors and secretes streptavidin, enabling precise delineation of invasive tumor margins with prolonged signal retention.
Dohee Lee +14 more
wiley +1 more source
Quantitative determination of intracellular miRNA content using dual gold and iron nanoreporters and single particle ICP-ToF-MS. [PDF]
Mikrochim ActaGonzález Morales S +4 more
europepmc +1 more source
Bioactive Glass Microscaffolds Fabricated by Two‐Photon Lithography
Advanced Materials, EarlyView.Microstructuring of bioactive glasses offers great potential to influence cell behavior for bone tissue engineering. By utilizing two‐photon lithography of a nanocomposite and thermal post‐processing, single‐micron features and complex structures are achieved.
Leonhard Hambitzer +7 more
wiley +1 more source