Results 71 to 80 of about 46,543 (177)

Novel 3D‐Printed Biophotonic Scaffold Displaying Luminescence under Near‐Infrared Light for Photopharmacological Activation and Biological Signaling Compound Release

Advanced Healthcare Materials, EarlyView.
Despite significant efforts in developing novel biomaterials to regenerate tissue, only a few of them have successfully reached clinical use. It has become clear that the next generation of biomaterials must be multifunctional. Smart biomaterials can respond to environmental or external stimuli, interact in a spatial‐temporal manner, and trigger ...
Sonya Ghanavati, Ekin Opar, Virginia Alessandra Gobbo, Carlo Matera, Fabio Riefolo, Rossella Castagna, Julien Colombelli, Andrew Draganski, Joshua Baggott, Mika Lastusaari, Pau Gorostiza, Laeticia Petit, Jonathan Massera   +12 more
wiley   +1 more source

RIPK2 induces docetaxel resistance in prostate cancer through the NF-κB/P-gp signaling pathway. [PDF]

PLoS One
Xing S, Xu Z, Zeng S, Yue M, Xing W, Liu Q.   +5 more
europepmc   +1 more source

Microphysiological Systems of Lymphatics and Immune Organs

Advanced Healthcare Materials, EarlyView.
This review surveys recent progress in engineering lymphatic microenvironments and immune organoids within microphysiological systems, emphasizing innovative strategies to recreate the biochemical and biophysical complexity of native lymphatic tissues.
Ishita Jain, Ankur Singh, Andrés J. García   +2 more
wiley   +1 more source

From ideal to practical: Heterogeneity of student-generated variant lists highlights hidden reproducibility gaps. [PDF]

PLoS Comput Biol
Ertürk RA, Emül AA, Darendeli-Kiraz BN, Sarı FZ, Ergün MA, Baysan M.   +5 more
europepmc   +1 more source

Development of a Synthetic 3D Platform for Compartmentalized Kidney In Vitro Disease Modeling

Advanced Healthcare Materials, EarlyView.
A fully synthetic, compartmentalized 3D kidney disease model is introduced. The kidney model combines a PEG‐based hydrogel matrix with anisotropic, enzymatically degradable rod‐shaped microgels to spatially arrange a triple co‐culture of key renal epithelial, endothelial, and fibroblast cells.
Ninon Möhl, Daphne Bouwens, Johanna Abele, Aline Hans, Tanja Topic, Daniel Günther, Jitske Jansen, Rafael Kramann, Laura De Laporte   +8 more
wiley   +1 more source

GMrepo v3: a curated human gut microbiome database with expanded disease coverage and enhanced cross-dataset biomarker analysis. [PDF]

Nucleic Acids Res
Liu C, Wang X, Zhang Z, Wang W, Wang T, Zhao Y, Wang M, Chen WH.   +7 more
europepmc   +1 more source

Enhancing Magnetic Hyperthermia at the Cell Membrane by Anchoring 92R‐Functionalized Magnetic Nanoparticles to Low‐Endocytic CCR9 Surface Receptors

Advanced Healthcare Materials, EarlyView.
We present a strategy to enhance magnetic hyperthermia therapy by modulating nanoparticle–cell interactions. Antibody‐functionalized magnetic nanoparticles targeting the low‐internalizing CCR9 receptor enable spatially controlled membrane anchoring, reducing aggregation and maximizing heat generation under alternating magnetic fields.
David Egea‐Benavente, Isabel Corraliza‐Gorjón, Thomas S. van Zanten, María del Puerto Morales, Leonor Kremer, Domingo F. Barber   +5 more
wiley   +1 more source

Cell2Read: an automated workflow to generate sequencing-ready DNA libraries from human cell suspensions. [PDF]

Biol Methods Protoc
Whitehead K, Planchak S, Williams T, Xia J, Park S, Hernandez Moyers A, Shah S, Bwanali L, Tripathi A.   +8 more
europepmc   +1 more source

A 3D Bioprinted Spheroid‐Laden dECM‐Enriched Osteosarcoma Model for Enhanced Drug Testing and Therapeutic Discovery

Advanced Healthcare Materials, EarlyView.
A 3D biomimetic OS model was developed by bioprinting an OS‐cell‐derived dECM‐enriched bioink with OS spheroids incorporated. The model showed upregulation of known OS prognostic markers and increased resistance to doxorubicin, compared to 2D cultures and scaffold‐free spheroids, making this a more clinically relevant platform for drug discovery ...
Margarida F. Domingues, Maria Catarina Carreira, Mafalda S. Santos, Daniela Pacheco, Frederico Castelo Ferreira, Paola Sanjuan‐Alberte, João Carlos Silva   +6 more
wiley   +1 more source

Development of a decision tree diagram for classifying study designs in tumour pathology research: a multidisciplinary approach. [PDF]

J Pathol Clin Res
Craciun OM, García-Ovejero E, Campbell F, Montes-Mota M, Holdenrieder S, Trulson I, Worf K, Gabriel S, Kowalewska M, Michalek I, Maslova K, Taraszkiewicz L, Del Águila J, Colling R, Tan PH, Goldman-Lévy G, Giesen C, Cierco Jimenez R, Lokuhetty D, Cree IA, Indave I, Pérez Gómez B, Chechlińska M, Pollán Santamaría M, Plans-Beriso E, WCT EVI MAP Project Team.   +25 more
europepmc   +1 more source