Results 151 to 160 of about 63,696 (324)

VDLIN: A Deep Learning‐Based Platform for Methylcobalamin‐Inspired Immunomodulatory Compound Screening

Advanced Science, EarlyView.
Using the convolutional neural network model VDLIN, Co7 is identified as a promising therapeutic candidate. Co7 demonstrates distinct advantages over MCB by effectively balancing anti‐inflammatory and immune‐stimulatory functions, making it a potential novel approach for immune modulation.
Xuefei Guo, Yang Zhao, Xianle Rong, Chenxi Niu, Shiyu Hu, Qiang Liu, Fuping You   +6 more
wiley   +1 more source

An Allele of Glutamate Formiminotransferase Triggers 5‐Methyl‐Tetrahydrofolate‐to‐MeFox Conversion and Facilitates Folate Biofortification in Maize

Advanced Science, EarlyView.
This work demonstrates the distinct roles of the glutamate formiminotransferase (GFT) enzyme in plants. The GFT triggers the conversion of 5‐methyl‐tetrahydrofolate to MeFox in plants, a process distinct from its role as a formiminotransferase in mammals.
Tong Lian, Wenzhu Guo, Yanjing Wang, Weiwei Wen, Weixuan Wang, Ling Jiang, Qiuju Liang, Ji'an Liu, Haijun Liu, Yuan Xue, Lixu Pan, Qiaoquan Liu, Ping Yin, Delin Zhang, Jianbing Yan, Chunyi Zhang   +15 more
wiley   +1 more source

Life Factors and Melanoma: From the Macroscopic State to the Molecular Mechanism

Advanced Science, EarlyView.
Melanoma, an aggressive skin cancer, arises from dynamic interactions between genetic, environmental, and lifestyle factors. This review explores how age, gender, obesity, diet, exercise, smoking, alcohol, UV exposure, circadian rhythms, and medications influence melanoma risk and progression.
Hanbin Wang, Hengxiang Zhang, Yuqi Zhou, Chunying Li, Weinan Guo   +4 more
wiley   +1 more source

The Mitochondrial Protein RESISTANCE to APHIDS 9 Interacts with S40 to Resist Aphid Infestation by Modulating Reactive Oxygen Species Homeostasis in Maize (Zea mays)

Advanced Science, EarlyView.
This study identifies the mitochondrial protein RTA9, a member of the Domain of Unknown Function 641 family, together with its partner S40, as key regulators of aphid resistance in maize. RTA9 promotes S40 degradation and modulates reactive oxygen species accumulation.
Chuanhong Wang, Xinqiao Zhang, Zhen Tao, Lei Wang, Shijie Huang, Tengyue Wang, Yibing Zhao, Jinghui Dong, Jing Ma, Chang Chang, Xingzhi Chen, Ning Lin, Peijin Li   +12 more
wiley   +1 more source

Spatiotemporal Characterization of the Functional MRI Latency Structure with Respect to Neural Signaling and Brain Hierarchy

Advanced Science, EarlyView.
Resting‐state fMRI captures intrinsic brain activity, yet the physical significance of latency structures remains unclear. In this study, the spatiotemporal properties of fMRI‐derived latency structures are examined by linking them to biophysical model‐based neural functions, intrinsic neural timescales, and functional gradients.
Hyoungshin Choi, Yeongjun Park, Jong‐eun Lee, Sunghun Kim, Bo‐yong Park, Hyunjin Park   +5 more
wiley   +1 more source

ZnO Quantum Dots@CsPbBr3 Poly‐Heterocrystalline Film Enables High‐Performance Floating‐Gate Transistor Arrays for Edge Computing

Advanced Science, EarlyView.
The ZnO QDs@CsPbBr3 poly‐heterocrystalline film, featuring a semi‐coherent interface, delivers high electrical conductivity and excellent photoelectric properties. Functioning as a floating gate in photosensitive transistors, it enables high hole storage at 1 V and achieves a conductivity ratio of ≈3.57×105.
Jiajun Xu, Bo Tong, Nian Dai, Tongjian Liu, Zhibo Liu, Dingdong Zhang, Yan Liang, Song Qiu, Lai‐Peng Ma, Jinhong Du   +9 more
wiley   +1 more source

Optimal Penalized Function-on-Function Regression under a Reproducing Kernel Hilbert Space Framework. [PDF]

J Am Stat Assoc, 2018
Sun X, Du P, Wang X, Ma P.
europepmc   +1 more source

Continuous Physics‐Informed Learning Expedited Battery Mechanism Decoupling

Advanced Science, EarlyView.
A battery modeling framework combining dual neural networks with physical prior is presented to track internal mechanisms, decouple overpotential components, and early predict aging trajectories using only DC data, eliminating the need for additional measurements.
Shanling Ji, Jun Yuan, Bojing Zhang, Aleksei Sanin, Leon Merker, Zhisheng Zhang, Jianxiong Zhu, Helge Sören Stein   +7 more
wiley   +1 more source

Biologically-Inspired Spike-Based Automatic Speech Recognition of Isolated Digits Over a Reproducing Kernel Hilbert Space. [PDF]

Front Neurosci, 2018
Li K, Príncipe JC.
europepmc   +1 more source

Holomorphic reproducing kernel for Kohn-Nierenberg domains in $\mathsf{C}^2$.

, 1988
John Erik Fornæss, Jan Wiegerinck
openalex   +2 more sources