Results 101 to 110 of about 2,155,020 (292)
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva +5 more
wiley +1 more source
Reproductive and health-related hazards of Lindane exposure in Aral sea area
Background: The Aral Sea problem arises after improper regulation of the water from cross-borders river and heavy application of the pesticides over the cotton fields in the area. Objectives: This review article was designed to highlight the reproductive
Aru Balmagambetova +5 more
doaj +1 more source
In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka +11 more
wiley +1 more source
Concise Review of Nickel Human Health Toxicology and Ecotoxicology
Nickel (Ni) metal and Ni compounds are widely used in applications like stainless steel, alloys, and batteries. Nickel is a naturally occurring element in water, soil, air, and living organisms, and is essential to microorganisms and plants.
Samuel Buxton +6 more
doaj +1 more source
Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Population and Reproductive Health [PDF]
Outlines the foundation's grantmaking strategies to reduce maternal mortality and morbidity and to advance youths' sexual and reproductive health and rights.
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Length at First Maturity, Spawning TIME, and Reproductive Output in the Females of Hamilton\u27s Anchovy (Thryssa Hamiltonii Gray, 1835) [PDF]
The Hamilton\u27s anchovy (Thryssa hamiltonii Gray, 1835) is one of main target species in Indonesian small pelagic fishery. This engraulids member is characterized by short lifespan and fast reproductive cycle.
Dewi, N. N. (Nina) +2 more
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The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li +2 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
BackgroundIn sub-Saharan African countries, including Ethiopia, the utilization of sexual and reproductive health information during adolescence is considered to be low.
Adera Debella +18 more
doaj +1 more source

