Results 231 to 240 of about 2,155,020 (292)
From Preservation to Creation: The Expanding Frontier of Fertility Preservation - Proceedings of the 2<sup>nd</sup> Montreux Reproductive Summit, 29-30 August 2025. [PDF]
Vallée A +15 more
europepmc +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
The Downward Floral Orientation in <i>Polygonatum cyrtonema</i> Enhances Pollination Efficiency and Reproductive Fitness. [PDF]
Tang J, Li DF, Ge XX, Xu YJ, Shao JW.
europepmc +1 more source
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute +4 more
wiley +1 more source
Construction, validation, and nitrogen nutrition diagnosis of a critical nitrogen concentration model for cotton. [PDF]
Qin Y +7 more
europepmc +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Knowledge and Attitude Toward Interpregnancy Interval and Its Impact on Women's Health. [PDF]
Jamil A, Mahmood H.
europepmc +1 more source
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova +14 more
wiley +1 more source
Precautions for polygenic embryo selection: prohibition or cautious use. [PDF]
Ishii T.
europepmc +1 more source

