Results 101 to 110 of about 21,182 (281)

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

open access: yesMolecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi   +14 more
wiley   +1 more source

The evolution and prevalence of reproductive assurance in the genus Lachenalia

open access: yes, 2013
Since its proposal by Darwin (1876), the concept of reproductive assurance (RA) has been much discussed, modified and tested. It is hypothesized to occur under pollen- and/or mate-limitation, each of which can arise in a multitude of manners, and RA ...
Rink, Ariella
core  

Greater reproductive assurance of asexual plant compared to sexual relative in a low density sympatric population – experimental evidence for pollen limitation

open access: yes, 2021
This dataset contains data from a common garden experiment described in the paper: "Mráz P, Mrázová V. 2021. Greater reproductive assurance of asexual plant compared to sexual relative in a low density sympatric population – experimental evidence for ...
Mrázová, Viera, Mráz, Patrik
core   +1 more source

Functional androdioecy in critically endangered Gymnocladus assamicus (Leguminosae) in the Eastern Himalayan Region of Northeast India.

open access: yesPLoS ONE, 2014
Gymnocladus assamicus is a critically endangered tree species endemic to Northeast India, and shows sexual dimorphism with male and hermaphrodite flowers on separate trees. We studied phenology, reproductive biology and mating system of the species.
Baharul Islam Choudhury   +2 more
doaj   +1 more source

Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma

open access: yesMolecular Oncology, EarlyView.
Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski   +10 more
wiley   +1 more source

Koenigia medogensis (Polygonaceae: Persicarieae), a Distinct New Species From Xizang, Southwestern China

open access: yesEcology and Evolution
Koenigia medogensis, a distinctive new species discovered in Medog County, southeastern Xizang, China, is here described and illustrated. The generic placement of this species was validated through integrated morphological and palynological observations,
Xiao‐Ting Xie   +6 more
doaj   +1 more source

ZW4864‐mediated inhibition of the β‐catenin/BCL9/BCL9L complex reveals therapeutic potential in bladder cancer

open access: yesMolecular Oncology, EarlyView.
BCL9 and BCL9L drive bladder cancer progression by enhancing β‐catenin signaling, promoting proliferation, migration, invasion, and organoid growth. Genetic depletion of BCL9(L) suppresses malignant phenotypes, while pharmacological disruption of the β‐catenin/BCL9(L) complex with ZW4864 inhibits canonical Wnt signaling and tumor‐associated cellular ...
Roland Kotolloshi   +11 more
wiley   +1 more source

Do the benefits of polyandry scale with outbreeding?

open access: yes, 2015
There have been many potential explanations put forward as to why polyandry often persists despite the multiple costs it can inflict on females. One such explanation is avoidance of costs associated with mating with genetically incompatible males ...
Burdfield-Steel, Emily Rose   +4 more
core   +1 more source

Uncertain pollination environment promotes the evolution of a stable mixed reproductive system in the self-incompatible Hypochaeris salzmanniana (Asteraceae)

open access: yes, 2017
International audienceBackground and aims The transition from outcrossing to selfing is a repeated pattern in angiosperm diversification and according to general theory this transition should occur quickly and mixed reproductive systems should be ...
Berjano, Regina   +17 more
core   +2 more sources

Bee pollination in the shadows: The role of pseudopollen and agamospermy in the mycoheterotrophic orchid Gastrodia elata

open access: yesPlants, People, Planet
Societal Impact Statement The family Orchidaceae is renowned for its reliance on specialized pollinators and mycorrhizal symbioses. This study examined how the nonphotosynthetic orchid Gastrodia elata thrives on the dim forest floor, focusing on its ...
Kenji Suetsugu, Takenori Yamamoto
doaj   +1 more source

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