Results 131 to 140 of about 21,182 (281)

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Reproductive system of a mixed-mating plant responds to climate perturbation by increased selfing

, 2013
How plants respond to climatic perturbations, which are forecasted to increase in frequency and intensity, is difficult to predict because of the buffering effects of plasticity.
Husband, B. C., MacDougall, A. S., MacDougall, AS, Jones, N. T., Jones, NT, Husband, BC   +5 more
core   +1 more source

Identifying gene expression signatures for risk stratification of postoperative adjuvant chemotherapy in colorectal cancer

FEBS Open Bio, EarlyView.
A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo, Keisuke Okuno, Shuichi Watanabe, Sakiko Oba, Hiroyasu Kagawa, Masanori Tokunaga, Daisuke Ban, Yusuke Kinugasa   +7 more
wiley   +1 more source

The empowerment of pregnant women in Tonekabon, Iran

Caspian Journal of Reproductive Medicine, 2016
Background: Pregnant women empowerment is viewed by policy makers and health care practitioners as a mechanism to help pregnant women adapt to physical and psychological changes after pregnancy, and gain a satisfactory experience of childbirth.
Leila Hajipour, Ali Montazeri, Zahra Mohtasham Amiri, Monirolsadat Hosseini Tabaghdehi, Farideh Mohsenzadeh Ledari   +4 more
doaj  

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Molecular dynamics simulations of positively selected codons in FcγRI reveal novel biochemical binding properties

FEBS Open Bio, EarlyView.
Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young, Omar Arias‐Gaguancela, Fiona Gibson, Morgan Grainger, Jodie Score, Amit Nathubhai, Mauricio Cafiero, Lee Richard Machado   +7 more
wiley   +1 more source

Quality control and quality assurance in the IVF laboratory

, 2022
The most critical outcome factors of an in vitro fertilization (IVF) laboratory are pregnancy results and live birth rates. For these successful outcomes, the performance of the IVF laboratory is of compulsory necessity.
Şişmanoğlu, Alper
core  

Major depression among pregnant women attending a tertiary teaching hospital in Northern Uganda assessed using DSM-V criteria

BMC Pregnancy and Childbirth
Background Major depression (MD) during pregnancy complicates maternal and neonatal outcomes. Despite its significant impact, there is a lack of evidence on the prevalence and associated factors of MD among pregnant women in Uganda.
Jerom Okot, Henry Ochola, Nozuko P. Blasich, Michael Job Aeku, Pebalo Francis Pebolo, Felix Bongomin, Simple Ouma   +6 more
doaj   +1 more source

Acute caffeine treatment protects the developing retina from ischemia‐induced cell death

FEBS Open Bio, EarlyView.
Caffeine reduces cell death in the developing retina under ischemia (OGD). This effect does not involve BDNF upregulation or antioxidant pathways (NRF2/VEGF). Neuroprotection occurs mainly through adenosine A2A receptor antagonism, decreasing glutamate release and excitotoxicity, highlighting caffeine's potential as an acute neuroprotective agent in ...
Amanda Alves Nascimento, Danniel Pereira‐Figueiredo, Gabriella Grossi de Lima Dias, Gabriel Ferreira dos Santos, Mariana Rodrigues Pereira, Rafael Brito, Karin C Calaza   +6 more
wiley   +1 more source

Multi-Dimensional Investigation of Factors Affecting Peer Educator Self-Assurance in Teaching Adolescent Sexual and Reproductive Health

Purpose: to examine the factors affecting the self-confidence of peer educators. Design/Methodology/Approach: a correlational descriptive study utilizing the SEM method, conducted with 216 health students.
Qomaruddin, Mochammad Bagus, Afridah, Wiwik, Martiana, Tri, Widiyanti, Prihartini   +3 more
core   +1 more source