Results 171 to 180 of about 2,335,827 (339)

Anopheline Reproductive Biology: Impacts on Vectorial Capacity and Potential Avenues for Malaria Control.

open access: yesCold Spring Harbor Perspectives in Medicine, 2017
Sara N. Mitchell, F. Catteruccia
semanticscholar   +1 more source

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

A splice site variant in MADD affects hormone expression in pancreatic β cells and pituitary gonadotropes

open access: yesJCI Insight
MAPK activating death domain (MADD) is a multifunctional protein regulating small GTPases RAB3 and RAB27, MAPK signaling, and cell survival. Polymorphisms in the MADD locus are associated with glycemic traits, but patients with biallelic variants in MADD
Kristiina Pulli   +17 more
doaj   +1 more source

Reproductive biology and anatomy of ammonites. [PDF]

open access: yesSci Rep
Klug C   +6 more
europepmc   +1 more source

Microphysiologic systems in female reproductive biology

open access: yesExperimental biology and medicine, 2017
Alexandria N. Young   +3 more
semanticscholar   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Treg cells promote decidual vascular remodeling and modulate uterine NK cells in pregnant mice

open access: yesJCI Insight
Regulatory T (Treg) cells are essential for maternal immune tolerance of the fetus and placenta. In preeclampsia, aberrant Treg cell tolerance is implicated, but how Treg cells affect the uterine vascular dysfunction thought to precede placental ...
Shanna L. Hosking   +12 more
doaj   +1 more source

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