Results 161 to 170 of about 477,223 (305)

High Co-infection Status of Novel Porcine Parvovirus 7 With Porcine Circovirus 3 in Sows That Experienced Reproductive Failure. [PDF]

Front Vet Sci, 2021
Mai J, Wang D, Zou Y, Zhang S, Meng C, Wang A, Wang N.   +6 more
europepmc   +1 more source

Meta‐analysis fails to show any correlation between protein abundance and ubiquitination changes

FEBS Open Bio, EarlyView.
We analyzed over 50 published proteomics datasets to explore the relationship between protein levels and ubiquitination changes across multiple experimental conditions and biological systems. Although ubiquitination is often associated with protein degradation, our analysis shows that changes in ubiquitination do not globally correlate with changes in ...
Nerea Osinalde, Unai Alduntzin, Gorka Prieto, Ugo Mayor   +3 more
wiley   +1 more source

Biochemical and Hepatic Determinants of Reproductive Failure in Reptiles: A Review of Dystocia Pathophysiology and Management. [PDF]

Vet Sci
Morel M, Gumpenberger M, Kempf H, Green S, Nederlof RA, Bakker J.   +5 more
europepmc   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Distinct Suppression of Prednisone on Endometrial Immune Cells in Women With Reproductive Failure. [PDF]

Am J Reprod Immunol
Chen L, Chen X, Xu Q, Li JJX, Yang WJ, Wu H, Wang CC, Fan X, Ji J, Chung JPW, Li M, Li TC, Zhang T.   +12 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Correction: Recurrent reproductive failure and celiac genetic susceptibility, a leading role of gluten. [PDF]

Front Immunol
de la Fuente-Munoz E, Fernández-Arquero M, Subhi-Issa N, Guevara-Hoyer K, Suárez LP, Laborda RG, Sánchez M, Ochoa-Grullón J, Guzmán-Fulgencio M, Villegas Á, Mansilla MD, Pérez N, Cornudella RS, Gastañaga-Holguera T, Urrutia MC, García IC, Sánchez-Ramón S.   +16 more
europepmc   +1 more source

Proteasomal degradation of intracellularly expressed Amblyomin‐X limits suicide gene therapy potential in melanoma cells

FEBS Open Bio, EarlyView.
This study explores the feasibility of expressing the antitumoral protein Amblyomin‐X through a suicide gene therapy approach and investigates its intracellular fate after gene delivery. Although the gene is efficiently expressed, melanoma cells rapidly degrade the Amblyomin‐X protein via proteasome activity.
Victor Dal Posolo Cinel, Carlos DeOcesano Pereira, Aline Ramos Maia Lobba, Melissa Regina Fessel, Ana Marisa Chudzinski‐Tavassi   +4 more
wiley   +1 more source

Worms and reproductive failure: First evidence of transplacental <i>Halicephalobus</i> transmission leading to repeated equine abortion. [PDF]

Curr Res Parasitol Vector Borne Dis
Springer A, Krüger C, Strube C, Steinhauer D.   +3 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source