Results 1 to 10 of about 12,718,117 (310)

BDNF secreted by mesenchymal stem cells improves aged oocyte quality and development potential by activating the ERK1/2 pathway

open access: yesCell Communication and Signaling
Background Reduced oocyte quality is a key factor in age-related fertility decline, and there are no effective treatments available. The secretome of mesenchymal stem cells (MSC-sec) contains various bioactive factors and has the potential to improve ...
Jing Zhou   +11 more
doaj   +1 more source

Reproductive health and rheumatoid arthritis

open access: yesBMC Rheumatology
Abstract Introduction: The prevalence of Rheumatoid Arthritis (RA) has been steadily increasing over the last thirty years, particularly among women. Due to the conflicting results of various studies on the link between rheumatoid arthritis and reproductive health, we have undertaken this study to explore their relationship.
Mohammad Erfan Ranjbaran, Maryam Kazemi
openaire   +3 more sources

Rhapontigenin alleviates cellular senescence and physiological aging by upregulating sirt1 and promoting autophagy

open access: yesChinese Medicine
Background Aging is characterized by cellular senescence, inflammation, and physiological decline. Currently available antiaging therapies often have limitations due to their toxicity and off-target effects.
Shuang Liu   +9 more
doaj   +1 more source

Elevated maternal pre-transfer serum lipid peroxidation is associated with implantation failure and early pregnancy loss

open access: yesBMC Medicine
Background Embryo implantation failure and early pregnancy loss remain significant challenges in assisted reproductive technology (ART). Lipid peroxidation is known to be involved in reproductive physiology.
Zhangwei Jia   +9 more
doaj   +1 more source

BDNF secreted by mesenchymal stem cells ameliorates the accelerated meiotic progression in aged mouse oocytes by activating the PI3K/AKT pathway

open access: yesStem Cell Research & Therapy
Background Oocyte aneuploidy is a major contributor to age-related fertility decline, but the effective treatments are still unavailable. The spindle assembly checkpoint (SAC), which functions to maintain chromosomal euploidy in oocytes, may become ...
Xin Mi   +9 more
doaj   +1 more source

Associations between organophosphate flame retardants and risk for nonsyndromic cleft lip and/or palate in offspring

open access: yesEnvironmental Sciences Europe
Introduction Nonsyndromic cleft lip and/or palate (NSCL/P) is a common congenital malformation with a complex etiology involving many environmental factors. Organophosphate flame retardants (OPFRs) are a class of emerging contaminants that are associated
Shujian Lin   +9 more
doaj   +1 more source

Exploration of the dynamic regulation of the hypothalamic-pituitary-ovarian axis during the estrous cycle

open access: yesJournal of Ovarian Research
Background One of the most challenging issues in current assisted reproductive technology is how to optimally counsel and treat patients with poor ovarian response (POR). However, current research predominantly emphasized the ovarian local changes during
Jian Sun   +6 more
doaj   +1 more source

Male Reproductive Health [PDF]

open access: yes, 2020
Wu W, Ziglioli F, Maestroni U
openaire   +1 more source

The threshold of estradiol level for fresh embryo transfer differs between blastocyst and cleavage‐stage embryo

open access: yesActa Obstetricia et Gynecologica Scandinavica
Introduction Ovarian stimulation can cause supraphysiological estradiol levels and adverse effects on endometrial receptivity. Since patients could undergo cleavage or blastocyst stage embryo transfer, the threshold value of peak estradiol level for each
Dingying Zhao   +12 more
doaj   +1 more source

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