Results 171 to 180 of about 1,087,820 (356)
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair+17 more
wiley +1 more source
Factors associated with poor well-being of infertile people: a cross-sectional study
Background: Infertility and its treatments have a negative impact on a person’s well-being. Purpose: This study aimed to determine the prevalence of poor well-being and associated factors among infertile people, in Tehran, Iran.
Saman Maroufizadeh+4 more
doaj
The effects of workplace hazards on female reproductive health. [PDF]
openalex +1 more source
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes+20 more
wiley +1 more source
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser+11 more
wiley +1 more source
A multi-center study was performed in Brazil, Chile, and Mexico to identify factors that may facilitate or hinder the introduction of emergency contraception (EC) as well as perceptions concerning emergency contraceptive pills.
Soledad Díaz+3 more
doaj
The use of twinning rates as a reproductive health monitor in England and Wales 1988-1996 [PDF]
W. H. James
openalex +1 more source