Results 171 to 180 of about 668,258 (314)

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

Russian survey highlights : results of the 2011 Russian Federation Reproductive Health Survey [PDF]

open access: yes
Infographic for: Reproductive health survey Russia 2011 : executive summary.russia-survey-2011-infographic ...

core  

Environmental estrogens and animal reproductive health: mechanisms, biomarkers, and intervention approaches. [PDF]

open access: yesJ Anim Sci Biotechnol
Liang S   +12 more
europepmc   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

open access: yesMolecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni   +11 more
wiley   +1 more source

Obesity and female reproductive health in Asian population. [PDF]

open access: yesObes Pillars
Panyakhamlerd K   +5 more
europepmc   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Sexual and reproductive health of adolescents in rural Nepal: Knowledge, attitudes and behavior

open access: yes, 2012
Background: Nepal has a relatively young and growing population, like most low-income countries. Recently, Nepal has accelerated its commitment to the International Conference on Population and Development (ICPD) Programme of Action by introducing a ...
Simkhada, Padam   +6 more
core  

GLP-1 receptor agonists and their implications for female reproductive health. [PDF]

open access: yesCase Rep Womens Health
Eagles E   +3 more
europepmc   +1 more source

Home - About - Disclaimer - Privacy