Results 131 to 140 of about 151,608 (253)

Reproductive Isolation [PDF]

, 2012
openaire   +1 more source

Patient therapy outcome modeling in cancer organoids is improved by cancer‐associated fibroblasts and organoid assembly convolution

Molecular Oncology, EarlyView.
Patient‐derived organoids (PDOs) from pancreatic, colorectal, and gastric cancers were used to evaluate standard and experimental therapies. Incorporating cancer‐associated fibroblasts (CAFs) into organoid cultures improved patient therapy outcome prediction.
Marcin Grochowski, Liudmyla Dolinchuk, Michał Jerzak, Albert Gandurski, Tomasz Grochowski, Weronika Wojtyś, Maciej Zadrożny, Wojciech Kaźmierczak, Małgorzata Lenarcik, Marta Matejak‐Górska, Radosław Samsel, Tomasz Olesiński, Dawid Walerych   +12 more
wiley   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Fine mapping and cloning of an intersubspecific reproductive isolation locus <i>MSHB1</i> in rice. [PDF]

Mol Breed
Wang X, Zhang Z, Zhao J, Chen M, Gong J, Han Y, Wei X, Huang X, Fan J.   +8 more
europepmc   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

Molecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller, Janina Müller, Efstathios‐Iason Vlachavas, Lukas Beumers, Lena Fleischhacker, Sara Burmester, Angelika Wörner, Sabine Karolus, Dominic Helm, Cindy Körner, Stefan Wiemann   +10 more
wiley   +1 more source

Radiation with reproductive isolation in the near-absence of phylogenetic signal. [PDF]

Sci Adv
Helmkampf M, Coulmance F, Heckwolf MJ, Acero P A, Balard A, Bista I, Dominguez OD, Frandsen PB, Torres-Oliva M, Santaquiteria A, Tavera J, Victor BC, Robertson DR, Betancur-R R, McMillan WO, Puebla O.   +15 more
europepmc   +1 more source

Epigenetics and reproductive isolation: a commentary on Westram et al., 2022. [PDF]

J Evol Biol, 2022
Planidin NP, de Carvalho CF, Feder JL, Gompert Z, Nosil P.   +4 more
europepmc   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Discovery of Genetically Distinct, Sympatric Coral Lineages With Temporal but Not Gametic Reproductive Isolation. [PDF]

Mol Ecol
Chamberland VF, Gómez-Corrales M, Marhaver KL, Bongaerts P, Latijnhouwers KRW, Vergara-Flórez DC, Snowden S, Sánchez JA, Vermeij MJA.   +8 more
europepmc   +1 more source

Morphological variation and reproductive isolation in the Hetaerina americana species complex. [PDF]

Sci Rep, 2022
Vega-Sánchez YM, Mendoza-Cuenca L, González-Rodríguez A.   +2 more
europepmc   +1 more source