Results 241 to 250 of about 403,470 (288)

Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham, Sahana Sathyanarayana, Charlotte B. Stewart, Robyn Iredale, Victoria Foster, Debra Galley, Mark Baker, Nicola Pavese   +7 more
wiley   +1 more source

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

In‐Depth Profiling Highlights the Effect of Efgartigimod on Peripheral Innate and Adaptive Immune Cells in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Myasthenia gravis (MG) is an autoimmune disorder characterized by antibody‐mediated complement activation. Efgartigimod, a neonatal Fc receptor (FcRn) antagonist, is approved for treating generalized MG (gMG). However, its modulatory effects on upstream innate and adaptive immune cells remain largely unexplored.
Lei Jin, Liu Dong, Ying Wang, Dingxian He, Chong Yan, Jianying Xi, Haoqin Jiang, Yu Shi, Ming Guan, Chongbo Zhao, Jie Song, Sushan Luo   +11 more
wiley   +1 more source

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The origins of reproductive isolation in plants

New Phytologist, 2015
SummaryReproductive isolation in plants occurs through multiple barriers that restrict gene flow between populations, but their origins remain uncertain. Work in the past decade has shown that postpollination barriers, such as the failure to form hybrid seeds or sterility of hybrid offspring, are often less strong than prepollination barriers. Evidence
Baack, Eric, Melo, Maria Clara, Rieseberg, Loreb H., Ortiz-Barrientos, Daniel   +3 more
openaire   +5 more sources

Reproductive isolation grows on trees

Trends in Ecology & Evolution, 2009
Despite rapid advances in the complementary fields of speciation genetics and molecular phylogenetics, little attention has been devoted to understanding how genetic changes associated with reproductive isolation accumulate across clades of species. We argue that comparative analyses of reproductive isolation QTL (quantitative trait loci) can generate ...
Leonie C, Moyle, Bret A, Payseur
openaire   +2 more sources

Reproductive isolation in Damselflies

Systematic Biology, 1974
Paulson, D. R. (Department of Zoology, University of Washington, Seattle, Washington 98195) 1974. Reproductive Isolation in Damselflies. Syst. Zool. 23:40-49.-Experiments were performed in the field on males of five species and females of ten species of damselflies (Odonata: Zygoptera: Coenagrionidae) to determine the relative importance of visual and ...
openaire   +1 more source

MOLECULAR CORRELATES OF REPRODUCTIVE ISOLATION

Evolution, 2002
Evolution of reproductive isolation as a byproduct of genetic divergence in isolated populations is the dominant (albeit not exclusive) mode of speciation in sexual animals. But little is known about the factors linking speciation to general divergence.
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ACO/CO reproductive isolation

2023
We ask if three decades and over 1 500 generations of divergent life history selection on age at reproduction has resulted in the evolution of reproductive isolation (RI) between laboratory populations of Drosophila melanogaster. We tested for premating, postmating-prezygotic and postzygotic reproductive isolation between 3 replicate population pairs ...
openaire   +1 more source

Reproductive isolation in birds: postcopulatory prezygotic barriers

Trends in Ecology & Evolution, 2007
Reproductive isolation is an important part of the speciation process. Recent studies of birds have highlighted not only the significance of postcopulatory postzygotic barriers, but also the almost complete absence of information about postcopulatory prezygotic barriers.
Birkhead, T.R., Brillard, Jean-Pierre
openaire   +4 more sources

Reproductive Isolation Concepts

2018
The notion that species are kinds of organisms delineated not by the decisions of the classifiers but by the reproductive behaviors and results of the organisms themselves is an old one. Modern views of species are widely known and discussed except for the ways that the most well-known reproductive isolation concept, the class of which we shall call ...
openaire   +2 more sources