Results 121 to 130 of about 397,094 (306)

Reproductive Medicine

Journal of Fertilization: In Vitro - IVF-Worldwide, Reproductive Medicine, Genetics & Stem Cell Biology, 2014
Marroquin Guillermo, Dabiri Tajudeen
openaire   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Perspectiva masculina acerca do aborto provocado

Revista de Saúde Pública
OBJETIVO: Analisar a perspectiva de homens de uma comunidade universitária que viviam em união legal ou consensual acerca do aborto provocado. MÉTODOS: Estudo descritivo de corte transversal em que se analisaram informações de 361 entrevistados ...
Graciana Alves Duarte, Augusta Thereza de Alvarenga, Maria José M Duarte Osis, Aníbal Faúndes, Ellen Hardy   +4 more
doaj  

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

Molecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu, Jianlei Zhao, Aaban Asfar Azmi, Avanti Gupte, Jenna Thibodeau, Shuang Liu, Jinli Yang, Guan Wang, Holly Edwards, Lisa A. Polin, Juiwanna Kushner, Sijana H. Dzinic, Kathryn White, Julie Boerner, Maik Hüttemann, Jay Yang, Yue Wang, Jeffrey W. Taub, Yubin Ge   +18 more
wiley   +1 more source

Prevenção de doenças sexualmente transmissíveis e Aids entre jogadores juniores

Revista de Saúde Pública
INTRODUÇÃO/ OBJETIVO: Os casos de Aids continuam crescendo entre os jovens, e existem poucos estudos para entender as especificidades da vulnerabilidade masculina no contexto jovem.
Wilson Aparecido Silva, Cassia Maria Buchalla, Vera Paiva, Maria do Rosário Dias de Oliveira Latorre, Ron Stall, Norman Hearst   +5 more
doaj  

Predictive modeling in reproductive medicine: Where will the future of artificial intelligence research take us? [PDF]

, 2020
Carol Lynn Curchoe, Jonas Malmsten, Charles L. Bormann, Hadi Shafiee, Adolfo Flores-Saiffe Farías, Gerardo Mendizabal, Alejandro Chávez-Badiola, Alexandros Sigaras, Hoor Alshubbar, J Chambost, Céline Jacques, Chris-Alexandre Pena, Andrew Drakeley, Thomas Fréour, Iman Hajirasouliha, Cristina Hickman, Olivier Elemento, Nikica Zaninović, Zev Rosenwaks   +18 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Therapeutic Application of Achillea millefolium L. in Female Reproductive Diseases from the Viewpoint of Persian Medicine and Current Medicine [PDF]

, 2019
Somayeh Zakeri, Narjes Gorji, Reihaneh Moeini, Zahra Memariani   +3 more
openalex   +1 more source

The need for business in reproductive medicine [PDF]

, 2021
Steven R. Lindheim, Mindy S. Christianson, Joseph S. Sanfilippo   +2 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source